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Effects of radial artery spasm prophylaxis on intracoronary vasomotor responses...

Schäufele, Tim; Menezes, Miguel Nobre; Schulte Steinberg, Benedict; Hubert, Astrid; Martínez Pereyra, Valeria; Arndt, Helene; Sechtem, Udo

Background: Invasive coronary angiography via the radial approach is commonly performed following radial artery spasm prophylaxis (RASP). It is however unknown, whether RASP influences the results of coronary spasm provocation testing performed after diagnostic angiography. We aimed to investigate the effects of RASP on vasomotor responses during intracoronary acetylcholine (ACh) testing. Methods: We retrospect...


Non-invasive derivation of instantaneous free-wave ratio from invasive coronary...

Oliveira, Catarina; Vilela, Marta; Silva Marques, João; Jorge, Claudia; Rodrigues, Tiago; Francisco, Ana Rita; Oliveira, Rita Marante de

Invasive coronary physiology is underused and carries risks/costs. Artificial Intelligence (AI) might enable non-invasive physiology from invasive coronary angiography (CAG), possibly outperforming humans, but has seldom been explored, especially for instantaneous wave-free Ratio (iFR). We aimed to develop binary iFR lesion classification AI models and compare them with human performance. single-center retrospe...


A narrative review of revascularization in chronic coronary syndrome/disease: c...

Nogueira-Garcia, Beatriz; Vilela, Marta; Oliveira, Catarina; Caldeira, Daniel; Martins, Ana Margarida; Menezes, Miguel Nobre

Ischemic heart disease represents a significant global burden of morbidity and mortality. While revascularization strategies are well defined in acute settings, there are uncertainties regarding chronic coronary artery disease treatment. Recent trials have raised doubts about the necessity of revascularization for "stable", chronic coronary syndromes or disease, leading to a shift towards a more conservative ap...


Interventional cardiology in cancer patients: a position paper from the Portugu...

Menezes, Miguel Nobre; Tavares da Silva, Marta; Magalhaes, Andreia; Melica, Bruno; Toste, Júlia Cristina; Calé, Rita; Almeida, Manuel; Fiuza, Manuela

The field of Cardio-Oncology has grown significantly, especially during the last decade. While awareness of cardiotoxicity due to cancer disease and/or therapies has greatly increased, much of the attention has focused on myocardial systolic disfunction and heart failure. However, coronary and structural heart disease are also a common issue in cancer patients and encompass the full spectrum of cardiotoxicity. ...


Coronary intravascular lithotripsy effectiveness and safety in a real-world cohort

Oliveira, Catarina; Vilela, Marta; Menezes, Miguel Nobre; Silva Marques, João; Jorge, Claudia; Rodrigues, Tiago; Almeida Duarte, José

Background: Coronary artery calcification is a predictor of adverse outcomes after percutaneous coronary intervention (PCI). Intravascular lithotripsy (IVL) is a promising tool for the treatment of calcified lesions. The aim of this study was to assess the effectiveness and safety of IVL. Methods: A single-center observational study of PCI procedure, with assessment of the outcomes of patients undergoing PCI us...


Old habits die hard: Can AI help bring coronary angiography Into the 21st Century?

Menezes, Miguel Nobre; Oliveira, Catarina Simões; Silva, João Lourenço; Silva, Beatriz Valente; Marques, João Silva; Guerreiro, Cláudio

Coronary angiography (CAG) was pioneered in the 1950s by Eduardo Coelho (who performed the first nonselective in vivo CAG in 1952 at the Santa Marta Hospital in Lisbon, Portugal) and Frank Mason Sones Jr (who performed the first selective CAG in vivo in 1958 at the Cleveland Clinic in Ohio, USA). Sones further developed the technique by contributing to the development of the C-arm, enabling multiangular views a...


Coronary artery calcium identified on non-gated chest CT scans: a wasted opport...

Valente Silva, Beatriz; Menezes, Miguel Nobre; Plácido, Rui; Jorge, Claudia; Rigueira, Joana; Garcia, Ana Beatriz; Martins, Ana Margarida

Background: Coronary artery calcium (CAC) evaluated on dedicated cardiac computed tomography (CT) is an independent predictor of cardiovascular events. This study aimed to evaluate the correlation between CAC detected on non-gated standard chest CT and coronary lesions on coronary angiography (CAG) and determine its impact on prognosis. Methods: Consecutive patients who underwent CAG due to acute coronary syndr...


Coronary X-ray angiography segmentation using Artificial Intelligence: a multic...

Menezes, Miguel Nobre; Silva, João Lourenço; Valente Silva, Beatriz; Rodrigues, Tiago; Guerreiro, Cláudio; Guedes, João Pedro; Santos, Manuel Oliveira

Introduction: We previously developed an artificial intelligence (AI) model for automatic coronary angiography (CAG) segmentation, using deep learning. To validate this approach, the model was applied to a new dataset and results are reported. Methods: Retrospective selection of patients undergoing CAG and percutaneous coronary intervention or invasive physiology assessment over a one month period from four cen...


Cardiovascular health metrics differ between individuals with and without cancer

Kobo, Ofer; Abramov, Dmitry; Fiuza, Manuela; Chew, Nicholas W. S.; Ng, Cheng Han; Parwani, Purvi; Menezes, Miguel Nobre; Thavendiranathan, Paaladinesh

Background: Although individuals with cancer experience high rates of cardiovascular morbidity, there are limited data on the potential differences in cardiovascular health (CVH) metrics between individuals with and without cancer. Methods and results: The National Health and Nutrition Examination Survey between 2015 and 2020 was queried to evaluate the prevalence of health metrics that comprise the American He...


Rapidly progressive coronary aneurysm: a rare case of isolated coronary vasculi...

Rodrigues, Tiago; Aguiar-Ricardo, Inês; Menezes, Miguel Nobre; Rigueira, Joana; Santos, Rafael; Fonseca, Valter R; Pinto, Fausto J.; Almeida, Ana G.

Isolated coronary arteritis without systemic involvement in adults is exceedingly rare. A 60-year-old patient developed recurrent non–ST-segment elevation myocardial infarctions for 1 year. After an initial coronary angiogram that was normal, serial angiograms showed de novo aneurysm formation. The patient responded favorably to corticosteroids, supporting the diagnosis of isolated coronary arteritis.


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