5 documents found, page 1 of 1
Re‐assessment of the risks to public health related to the genotoxicity of styr...
EFSA Panel on Food Contact Materials (FCM); Claude, Lambré; Crebelli, Riccardo; Silva, Maria Da; Grob, Konrad; Lampi, Evgenia; Milana, Maria RosariaThe EFSA Panel on Food Contact Materials (FCM) was requested by the European Commission to re‐evaluate the potential genotoxicity of styrene after oral exposure and its safety for use in plastic FCM with a specific migration limit (SML) of 40 μg/kg food. A rigorous assessment of the in vivo genotoxicity studies (i) provided by third parties, (ii) identified by a targeted literature search and (iii) reported in ...
Biomonitorização humana de micotoxinas no âmbito do projeto HBM4EU: um estudo s...
Alvito, Paula; Namorado, Sónia; Assunção, Ricardo; Bajard, Lola; Martins, Carla; Mengelers, Marcel; Mol, Hans; Van den Brand, Annick; Vasco, ElsaAs micotoxinas são toxinas naturais produzidas por fungos, apresentando efeitos tóxicos para o homem e para os animais. Reconhece-se, atualmente, que as alterações climáticas terão impacto na distribuição geográfica de algumas espécies de fungos produtores de micotoxinas o que se traduzirá, previsivelmente, num aumento da exposição humana a estes compostos. Pelas razões descritas, urge conhecer a atual exposiçã...
Human biomonitoring of mycotoxins under HBM4EU: update on key outputs
Alvito, Paula; Assunção, Ricardo; Bajard, Lola; Mol, Hans; Martins, Carla; Mengelers, Marcel; Namorado, Sónia; Vasco, Elsa; Van den Brand, AnnickThe European Human Biomonitoring Initiative (HBM4EU) is a project gathering 30 countries, funded under Horizon 2020 and running from 2017 until 2021. The goal of HBM4EU is to generate evidence on the current exposure of European citizens to chemicals and on their possible health effects to assess the associated risks. Following a systematic prioritization exercise, the mycotoxins Deoxynivalenol (DON) and Fumoni...
Biomarkers of effect as determined in human biomonitoring studies on hexavalent...
Ventura, Célia; Gomes, BC; Oberemm, Axel; Louro, Henriqueta; Huuskonen, Pasi; Mustieles, Vicente; Fernández, Mariana F.; Ndaw, Sophie; Mengelers, MarcelA number of human biomonitoring (HBM) studies have presented data on exposure to hexavalent chromium [Cr(VI)] and cadmium (Cd), but comparatively few include results on effect biomarkers. The latter are needed to identify associations between exposure and adverse outcomes (AOs) in order to assess public health implications. To support improved derivation of EU regulation and policy making, it is of great import...
Plan for development of case studies - Deliverable Report AD 15.1 WP 15 - Mixtu...
Kortemkamp, Andreas; Mengelers, Marcel; Vinggaard, Anne Marie; Silva, Maria João; Slamay, Remy; Vermeulen, Roel; Vlaanderen, Jelle; Ottenbros, IlseThis deliverable describes the activities in task 15.3 leading up to the development of cases studies for mixture health effects and outlines the proposed case studies. The proposed case studies are: · Developmental neurotoxicity beyond polybrominated diphenylethers · Heavy metals and nephrotoxicity · Anti-androgenic chemicals and male reproductive health · Chromium (VI), nickel and polycyclic aromatic hydrocar...