58 documents found, page 1 of 6
Deep Eutectic Systems: A Game Changer for Marine Bioactives Recovery
Amador, Sandro; Martins, Alice; Matias, Margarida; Pedrosa, Rui; Pinteus, SuseteThe extraction of bioactive compounds from marine natural products has gained increasing attention due to their diverse applications, such as in pharmaceuticals, nutraceuticals, and cosmetics. Yet, low extraction yields and toxicity associated with common solvents are a major bottleneck. Deep eutectic solvents (DESs) and natural deep eutectic solvents (NADESs) have emerged as promising green alternatives to con...
Oxidative Stability of Sunflower Oil Enriched with Fig Tree Leaves Bioactive Co...
Pinteus, Susete; Neves, Marta; Tecelão, Carla; Silva, Susana; Cruz, Alexandra; Bernardino, Susana; Mendes, Vasco; Vaz, Daniela; Campos, Maria JorgeThe pressure imposed by the increase of world’s population and climate change makes it imperative to find sustainable strategies to optimize food resources and decrease waste production based on circular economy principles. This work evaluated the potential of fig tree leaves to reduce the oxidation of sunflower oil when exposed to frying temperatures. The bioactive compounds extracted directly from fig tree le...
Sulfated polysaccharides from macroalgae: A simple roadmap for chemical charact...
Martins, Alice; Alves, Celso; Silva, Joana; Pinteus, Susete; Gaspar, Helena; Pedrosa, RuiThe marine environment presents itself as a treasure chest, full of a vast diversity of organisms yet to be explored. Among these organisms, macroalgae stand out as a major source of natural products due to their nature as primary producers and relevance in the sustainability of marine ecosystems. Sulfated polysaccharides (SPs) are a group of polymers biosynthesized by macroalgae, making up part of their cell w...
New insights into the dermocosmetic potential of the red seaweed Gelidium corneum
Matias, Margarida; Martins, Alice; Alves, Celso; Silva, Joana; Pinteus, Susete; Fitas, Manuel; Pinto, Pedro; Marto, Joana; Ribeiro, HelenaThis work addresses the potential of the red seaweed Gelidium corneum as a source of bioactive ingredients for skin health and wellness in response to the growing awareness regarding the significance of sustainable strategies in developing new nature-based dermocosmetic products. Hydroalcoholic extracts from the dried biomass were subjected to sequential liquid–liquid partitions, affording five different fracti...
Valorization of the red seaweed Gracilaria gracilis through a biorefinery approach
Martins, Alice; Pinto, Filipa R.; Barroso, Sónia; Pereira, Tatiana; Mouga, Teresa; Afonso, Clélia; Freitas, Marta V.; Pinteus, Susete; Pedrosa, RuiThe interest in seaweeds as an abundant feedstock to obtain valuable and multitarget bioactive ingredients is continuously growing. In this work, we explore the potential of Gracilaria gracilis, an edible red seaweed cultivated worldwide for its commercial interest as a source of agar and other ingredients for cosmetic, pharmacological, food, and feed applications. G. gracilis growth conditions were optimized t...
Disclosing the antitumour potential of the marine bromoditerpene sphaerococceno...
Alves, Celso; Silva, Joana; Afonso, Marta B; Guedes, Romina A.; Guedes, Rita C.; Alvariño, Rebeca; Pinteus, Susete; Gaspar, Helena; Goettert, Márcia I.Nature has revealed to be a key source of innovative anticancer drugs. This study evaluated the antitumour potential of the marine bromoditerpene sphaerococcenol A on different cancer cellular models. Dose-response analyses (0.1-100 µM; 24 h) were accomplished in eight different tumour cell lines (A549, CACO-2, HCT-15, MCF-7, NCI-H226, PC-3, SH-SY5Y, SK-MEL-28). Deeper studies were conducted on MFC-7 cells, nam...
Disclosing the antitumour potential of the marine bromoditerpene sphaerococceno...
Alves, Celso; Silva, Joana; Afonso, Marta B.; Guedes, Romina A.; Guedes, Rita C.; Alvariño, Rebeca; Pinteus, Susete; Gaspar, Helena; Goettert, Marcia I.Nature has revealed to be a key source of innovative anticancer drugs. This study evaluated the antitumour potential of the marine bromoditerpene sphaerococcenol A on different cancer cellular models. Dose-response analyses (0.1–100 μM; 24 h) were accomplished in eight different tumour cell lines (A549, CACO-2, HCT-15, MCF-7, NCI-H226, PC-3, SH-SY5Y, SK-MEL-28). Deeper studies were conducted on MFC-7 cells, nam...
Antioxidant and antimicrobial potential of six Fucoids from the Mediterranean S...
De La Fuente, Gina; Pinteus, Susete; Silva, Joana; Alves, Celso; Pedrosa, RuiBACKGROUD: In recent years, research on the bioactive properties of macroalgae has increased, due to the great interest in exploring new products that can contribute to improve human health and wellbeing. In the present study, the antioxidant and antimicrobial potential of six different brown algae of the Fucales order were evaluated, namely Ericaria selaginoides, Ericaria amentacea, Gongolaria baccata, Gongola...
Exploring marine resources against neurological disorders: the neuroprotective ...
Silva, Joana; Alves, Celso; Susano, Patrícia; Martins, Alice; Pinteus, Susete; Gaspar, Helena; Alfonso, Amparo; Pedrosa, RuiOxidative stress is strongly involved in the pathogenesis of neurodegenerative diseases, like Parkinson´s disease (PD). Particularly, an excess of reactive oxygen species (ROS) released by the cells promotes an oxidative stress condition, which is a main cause of tissue injury leading to nervous system dysfunction. In this work, the antioxidant, neuroprotective and antiinflammatory activities of different fract...
Seaweed’s role in energetic transition: From environmental pollution challenges...
Pinteus, Susete; Susano, Patrícia; Alves, Celso; Silva, Joana; Martins, Alice; Pedrosa, RuiResulting from the growing human population and the long dependency on fossil-based energies, the planet is facing a critical rise in global temperature, which is affecting all ecosystem networks. With a growing consciousness this issue, the EU has defined several strategies towards environment sustainability, where biodiversity restoration and preservation, pollution reduction, circular economy, and energetic ...