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Accumulation of organotins in seafood leads to reproductive tract abnormalities...

Podratz, Priscila Lang; Merlo, Eduardo; Sena, Gabriela C.; Morozesk, Mariana; Bonomo, Marina Marques; Matsumoto, Silvia T.; Costa, Mércia Barcellos da

Organotins (OTs) are environmental contaminants used as biocides in antifouling paints that have been shown to be endocrine disrupters. However, studies evaluating the effects of OTs ccumulated in seafood (LNI) on reproductive health are particularly sparse. This study demonstrates that LNI leads to impairment in the reproductive tract of female rats, as the estrous cycle development, as well as for ovary and u...

Date: 2022   |   Origin: Oasisbr

Tributyltin chloride leads to adiposity and impairs metabolic functions in the ...

Bertuloso, Bruno Duarte; Podratz, Priscila Lang; Merlo, Eduardo; Araújo, Julia Fernandez Puñal de; Lima, Leandro Ceotto Freitas

Tributyltin chloride (TBT) is an environmental contaminant used in antifouling paints of boats Endocrine disruptor effects of TBT are well established in animal models. However, the adverse effects on metabolism are less well understood. The toxicity of TBT in the white adipose tissue (WAT), liver and pancreas of female rats were assessed. Animals were divided into control and TBT (0.1 mg/kg/day) groups. TBT in...

Date: 2022   |   Origin: Oasisbr

Tributyltin impacts in metabolic syndrome development through disruption of ang...

Ceotto Freitas-Lima, Leandro; Merlo, Eduardo; Campos Zicker, Marina; Navia-Pelaez, Juliana Maria; de Oliveira, Miriane

Made available in DSpace on 2022-04-29T08:45:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-15; White adipose tissue (WAT) dysfunction and obesity are a consequence of a low-grade inflammation state. These WAT irregularities could result from abnormal metabolic renin-angiotensin system (RAS) control. Recently, tributyltin (TBT) has been found to play a critical role in these metabolic irregulariti...

Date: 2022   |   Origin: Oasisbr

Tributyltin chloride leads to adiposity and impairs metabolic functions in the ...

Bertuloso, Bruno D.; Podratz, Priscila L.; Merlo, Eduardo; de Araújo, Julia F.P.; Lima, Leandro C.F.; de Miguel, Emilio C.; de Souza, Leticia N.

Made available in DSpace on 2022-04-29T08:44:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-05-09; Tributyltin chloride (TBT) is an environmental contaminant used in antifouling paints of boats. Endocrine disruptor effects of TBT are well established in animal models. However, the adverse effects on metabolism are less well understood. The toxicity of TBT in the white adipose tissue (WAT), liver and ...

Date: 2022   |   Origin: Oasisbr

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