8 documents found, page 1 of 1
Evaluation of the ACS NSQIP Surgical Risk Calculator in Elderly Patients Underg...
Sahara, K; Paredes, A; Merath, K; Tsilimigras, D; Bagante, F; Ratti, F; Pinto Marques, H; Soubrane, O; Beal, E; Lam, V; Poultsides, G; Popescu, IBackground: The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) surgical risk calculator (SRC) aims to help predict patient-specific risk for morbidity and mortality. The performance of the SRC among an elderly population undergoing curative-intent hepatectomy for hepatocellular carcinoma (HCC) remains unknown. Methods: Patients > 70 years of age who underwent hepatectomy ...
Hospital Variation in Textbook Outcomes Following Curative-Intent Resection of ...
Tsilimigras, D; Mehta, R; Merath, K; Bagante, F; Paredes, AZ; Farooq, A; Ratti, F; Pinto Marques, H; Silva, S; Soubrane, O; Lam, V; Poultsides, GBackground: Composite measures such as "Textbook Outcome" (TO) may be superior to individual quality metrics to assess surgical care and hospital performance. However, the incidence and factors associated with TO after resection of HCC remain poorly defined. Methods: Hospital variation in the rates of TO, factors associated with achieving a TO and the impact of TO on long-term survival following resection for H...
Effect of Surgical Margin Width on Patterns of Recurrence among Patients Underg...
Tsilimigras, D; Sahara, K; Moris, D; Hyer, J; Paredes, A; Bagante, F; Merath, K; Farooq, A; Ratti, F; Pinto Marques, H; Soubrane, O; Azoulay, D; Lam, VIntroduction: Although a positive surgical margin is a known prognostic factor for recurrence, the optimal surgical margin width in the context of an R0 resection for early-stage hepatocellular carcinoma (HCC) is still debated. The aim of the current study was to examine the impact of wide (> 1 cm) versus narrow (< 1 cm) surgical margin status on the incidence and recurrence patterns among patients with T1 HCC ...
Therapeutic Index Associated with Lymphadenectomy Among Patients with Intrahepa...
Sahara, K; Tsilimigras, D; Merath, K; Bagante, F; Guglielmi, A; Aldrighetti, L; Weiss, M; Bauer, T; Alexandrescu, S; Poultsides, G; Maithel, SBackground: Although lymph node metastasis (LNM) is an important prognostic indicator for patients with intrahepatic cholangiocarcinoma (ICC), the benefit and indication for lymphadenectomy remain unclear. Methods: Patients diagnosed with ICC between 1990 and 2016 were identified in the international multi-institutional dataset. To determine the survival benefit from lymphadenectomy, the therapeutic index was c...
Complications After Liver Surgery: a Benchmark Analysis
Bagante, F; Ruzzenente, A; Beal, E; Campagnaro, T; Merath, K; Conci, S; Akgül, O; Alexandrescu, S; Pinto Marques, H; Lam, V; Shen, F; Poultsides, GBackground: The best achievable short-term outcomes after liver surgery have not been identified. Several factors may influence the post-operative course of patients undergoing hepatectomy increasing the risk of post-operative complications. We sought to identify risk-adjusted benchmark values [BMV] for liver surgery. Methods: The National Surgery Quality Improvement Program (NSQIP) database was used to develop...
Impact of Body Mass Index on Tumor Recurrence Among Patients Undergoing Curativ...
Merath, K; Mehta, R; Hyer, JM; Bagante, F; Sahara, K; Alexandrescu, S; Pinto Marques, H; Aldrighetti, Luca; Maithel, SK; Pulitano, C; Weiss, MJBackground: The association between body mass index (BMI) and long-term outcomes of patients with ICC has not been well defined. We sought to define the presentation and oncologic outcomes of patients with ICC undergoing curative-intent resection, according to their BMI category. Methods: Patients who underwent resection of ICC were identified in a multi-institutional database. Patients were categorized as norm...
The Limitations of Standard Clinicopathologic Features to Accurately Risk-Strat...
Bagante, F; Merath, K; Squires, M; Weiss, M; Alexandrescu, S; Pinto Marques, H; Aldrighetti, L; Maithel, S; Pulitano, C; Bauer, T; Shen, FBackground: The ability to provide accurate prognostic data after hepatectomy for intrahepatic cholangiocarcinoma (ICC) remains poor. We sought to develop and validate a nomogram to predict survival, as well as investigate the clinical implications of underestimating patients' risk of recurrence. Methods: Patients undergoing curative-intent resection of ICC between 1990 and 2015 at 14 major hepatobiliary center...
Preoperative Prognostic Nutritional Index Predicts Survival of Patients with In...
Akgül, Ö; Bagante, F; Olsen, G; Cloyd, JM; Weiss, M; Merath, K; Alexandrescu, S; Pinto Marques, H; Aldrighetti, L; Maithel, SK; Pulitano, C; Bauer, TWBackground: Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy. We sought to examine the association between preoperative prognostic nutritional index (PNI) and long-term overall survival among patients with ICC who underwent curative-intent resection. Methods: Patients who underwent hepatectomy for ICC between 1990 and 2015 were identified using an international multi-institutional database. Cli...