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Seaweeds as Nutraceutical Elements and Drugs for Diabetes Mellitus: Future Pers...

Cotas, João; Lomartire, Silvia; Pereira, Leonel; Valado, Ana; Marques, J.; Gonçalves, Ana Marta

Diabetes mellitus is a chronic metabolic condition marked by high blood glucose levels caused by inadequate insulin synthesis or poor insulin use. This condition affects millions of individuals worldwide and is linked to a variety of consequences, including cardiovascular disease, neuropathy, nephropathy, and retinopathy. Diabetes therapy now focuses on controlling blood glucose levels through lifestyle changes...


Laboratory Assessment of the Effects of AGA@4life Multidisciplinary Interventio...

Lourenço, Ana Patrícia; Freitas, Catarina; Timóteo, Maria Helena; Soares, Maria; Figueiredo, João; Osório, Nádia; Valado, Ana; Trapali, Maria

Abstract: In recent years, the world’s aging population has increased, contributing to the development of age-related pathologies, which have been aggravated by physical inactivity and excessive fat intake. This study aimed to evaluate the effect of implementing a nutritional program (control group—CG) combined with exercise (intervention group—IG) on the inflammatory profile, MMPs, and TIMPs in a group of 34 e...


Algae-Derived Natural Products in Diabetes and Its Complications-Current Advanc...

Pereira, Leonel; Valado, Ana

Diabetes poses a significant global health challenge, necessitating innovative therapeutic strategies. Natural products and their derivatives have emerged as promising candidates for diabetes management due to their diverse compositions and pharmacological effects. Algae, in particular, have garnered attention for their potential as a source of bioactive compounds with anti-diabetic properties. This review offe...


The Seaweed Diet in Prevention and Treatment of the Neurodegenerative Diseases

Pereira, Leonel; Valado, Ana

Edible marine algae are rich in bioactive compounds and are, therefore, a source of bioavailable proteins, long chain polysaccharides that behave as low-calorie soluble fibers, metabolically necessary minerals, vitamins, polyunsaturated fatty acids, and antioxidants. Marine algae were used primarily as gelling agents and thickeners (phycocolloids) in food and pharmaceutical industries in the last century, but r...


On the Health Benefits vs. Risks of Seaweeds and Their Constituents: The Curiou...

Cotas, João; Pacheco, Diana; Araujo, Glacio Souza; Valado, Ana; Critchley, Alan T.; Pereira, Leonel

To exploit the nutraceutical and biomedical potential of selected seaweed-derived polymers in an economically viable way, it is necessary to analyze and understand their quality and yield fluctuations throughout the seasons. In this study, the seasonal polysaccharide yield and respective quality were evaluated in three selected seaweeds, namely the agarophyte Gracilaria gracilis, the carrageenophyte Calliblepha...



Bioanalytical approach-ageing, exercise and oxidative stress

Valado, Ana; Lopes, Diana; Osório, Nádia; Caseiro, Armando; Figueiredo, João; Patrício, Cristina; Pacheco, Maria Paula; Oostingh, Gertie Janneke

Abstract: Exercise interferes with the ageing, causing changes in markers of the antioxidant system, such as nitric oxide (NO) and uric acid. Aim: The objective of this study was to evaluate if regular exercise affects the ageing process by causing changes in the antioxidant markers, nitric oxide and uric acid, in individuals aged ≥ 65 years, subjected to an exercise plan. Methods: The study involved 12 partici...


Effect of Carrageenans on Vegetable Jelly in Humans with Hypercholesterolemia

Valado, Ana; Pereira, Maria; Caseiro, Armando; Figueiredo, João P.; Loureiro, Helena; Almeida, Carla; Cotas, João; Pereira, Leonel

Changes in lipid profile constitute the main risk factor for cardiovascular diseases. Algae extracted carrageenans are long-chain polysaccharides and their ability to form gels provides for the formation of vegetable jelly. The objective was to evaluate the bioactive potential of carrageenan (E407) in the lipid profile, after ingestion of jelly. A total of 30 volunteers of both sexes, aged 20-64 years and with ...


Effect of carrageenans on vegetable jelly in humans with hypercholesterolemia

Valado, Ana; Pereira, Maria; Caseiro, Armando; Figueiredo, João; Loureiro, Helena; Almeida, Carla; Cotas, João; Pereira, Leonel

Changes in lipid profile constitute the main risk factor for cardiovascular diseases. Algae extracted carrageenans are long-chain polysaccharides and their ability to form gels provides for the formation of vegetable jelly. The objective was to evaluate the bioactive potential of carrageenan (E407) in the lipid profile, after ingestion of jelly. A total of 30 volunteers of both sexes, aged 20-64 years and with ...


Antioxidant and antitumor potential of wild and IMTA-cultivated Osmundea pinnat...

Silva, J. Paulo; Alves, Celso; Pinteus, Susete; Silva, Joana; Valado, Ana; Pedrosa, Rui; Pereira, Leonel

Osmundea pinnatifida is a red edible seaweed known as pepper dulse. O. pinnatifida was cultivated in the farm of ALGAplus (Ílhavo, Portugal). This farm is integrated with a seabream and seabass commercial aquaculture and uses the nutrient-enriched water resultant from the fish production as its cultivation medium in the integrated multi-trophic aquaculture (IMTA) manner. Wild and IMTA-cultivated samples of O. p...

Date: 2019   |   Origin: IC-online

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