29 documents found, page 1 of 3
Inflammatory biomarkers and perinatal depression: a systematic review
Silva-Fernandes, Anabela; Conde, Ana; Marques, Margarida; Caparros-Gonzalez, Rafael A.; Fransson, Emma; Mesquita, Ana Raquel MarcelinoBackground: Approximately 10 to 20% of pregnant women worldwide experience perinatal depression (PND), a depressive episode with onset during pregnancy or after childbirth. We performed a systematic review to identify, summarize and discuss studies on inflammatory biomarkers described in relation to PND. Methods: Inclusion criteria defined the selection of observational studies written in English, French, Spani...
Non-invasive diagnosis and monitoring tool of children’s mental health: a point...
Cruz, Andrea; Vieira, Maria; Mesquita, Ana Raquel Marcelino; Sampaio, Adriana; Mendes-Pinto, Inês; Soares, Isabel; Freitas, Paulo P.Mental disorders are commonly featured as chronic conditions with often onset during childhood. In this context, inflammation has been associated with a higher risk of developing physical and mental health problems. Interleukin (IL)-6 is a key mediator of inflammatory responses and plays a pivotal role in immune and nervous system interaction. High levels of IL-6 during childhood are associated with mental prob...
Acute stress impairs reward learning in men
Carvalheiro, Joana; Conceição, Vasco A.; Mesquita, Ana Raquel Marcelino; Seara-Cardoso, AnaAcute stress is ubiquitous in everyday life, but the extent to which acute stress affects how people learn from the outcomes of their choices is still poorly understood. Here, we investigate how acute stress impacts reward and punishment learning in men using a reinforcement-learning task. Sixty-two male participants performed the task whilst under stress and control conditions. We observed that acute stress im...
Mothers' distress exposure and children's withdrawn behavior - A moderating rol...
Pinto, Raquel; Belsky, Jay; Baptista, Joana; Carvalho, Agostinho; Cunha, Cristina; Soares, Isabel; Mesquita, Ana Raquel MarcelinoThe dysregulation of the inflammatory response, including pro-inflammatory molecules, produces neuropsychiatric symptoms and depression-like behavior, including withdrawal from the physical and social environment. Genetic variants that enhance immune reactivity may thus increase inflammatory and withdrawn reactions to stress. Here we investigated a functional polymorphism of Interferon Gamma gene (IFNG +874 T >...
Links between reactive attachment disorder, caregiving and temperament: a diffe...
Corval, Ana Raquel Morais; Mesquita, Ana Raquel Marcelino; Soares, IsabelThe links between Reactive Attachment Disorder (RAD) and temperament received relatively little research attention, in spite of their clinical and social relevance. Children with RAD sustain disproportionate burdens of early adversity related to their caregiving environment. However, there seem to be important individual differences in susceptibility to adversity, since only a small number of children show sign...
Development and validation of an observational measure of symptoms of Reactive ...
Corval, Ana Raquel Morais; Belsky, Jay; Baptista, Joana; Mesquita, Ana Raquel Marcelino; Soares, IsabelReactive Attachment Disorder (RAD) is presumed to be a consequence of social neglect and deprivation of the kind particularly associated with institutional care. Despite its clinical relevance there is a lack of assessment tools for RAD based on the direct observation of child-caregiver interaction. Here we describe the development and validation of such a tool for use with preschool children, the Rating of Inh...
Agreement and Disagreement on Emotional and Behavioral Problems in a Sample of ...
Carneiro, Alexandra; Dias, Pedro; Pinto, Raquel; Baião, Rita Isabel Curto; Mesquita, Ana Raquel Marcelino; Soares, IsabelThe present study aimed to identify predictors of agreement and disagreement concerning emotional and behavioral problems reported by the mothers and teachers of preschool-aged children. Participants included 172 (89 boys) children, their mothers, and their preschool teachers. Mothers were asked to complete the Child Behavior Checklist for Ages 1½-5 (CBCL 1½-5), the Brief Symptom Inventory (BSI), and a sociodem...
Child's oxytocin response to mother-child interaction: The contribution of chil...
Baiao, Rita; Fearon, Pasco; Belsky, Jay; Baptista, Joana; Carneiro, Alexandra; Pinto, Raquel; Nogueira, Marlene; Oliveira, César João SantosThe oxytocinergic system is a primary biological system involved in regulating a child's needs for bonding and for protection from threats. It is responsive to social experiences in close relationships, though evidence across studies is not entirely consistent. Guided by previous literature, we investigated individual and environmental factors predicting and presumably affecting children's oxytocin (OT) respons...
Associations between fetal testosterone and pro–social tendencies, anxiety and ...
Osório, Ana Alexandra Caldas; do Egito, Júlia Horta Tabosa; Martins, Gabriela Carneiro; Kim, Chong Ae; Honjo, Rachel Sayuri; Sampaio, AdrianaObjective: Fetal testosterone (fT) has organizational effects on the developing human nervous system and can be reliably estimated by the ratio between the length of the second and fourth digits — 2D:4D. Previous studies reported altered patterns of fT in some developmental disabilities (e.g. ASD) relative to typically developing individuals (TD). Williams syndrome (WS) is a rare genetic disorder characterized ...
Helping Behavior in Rats (Rattus norvegicus) When an Escape Alternative Is Present
Carvalheiro, Joana; Seara-Cardoso, Ana; Mesquita, Ana Raquel Marcelino; de Sousa, Liliana; Oliveira, Pedro; Summavielle, Teresa; Magalhaes, AnaProsocial behavior in rats is known to occur in response to a familiar rat's distress, but the motivations underlying prosocial behavior remain elusive. In this study, we adapted the experimental setting of Ben-Ami Bartal, Decety, and Mason (2011) to explore different motivations behind helping behavior in adolescent rats. In the original setting, a free rat is placed in an arena where a cagemate is trapped ins...