3 documents found, page 1 of 1
In vitro evaluation of the curcumin against fluconazole-resistant strains of Ca...
Freitas, Daniel Domingues; Silva, Cecília Rocha da; Andrade Neto, João Batista de; Campos, Rosana de Sousa; Sampaio, Letícia SerpaThe isolates of Candida spp. and Cryptococcus neoformans were inhibited by curcumin, with different degrees of inhibition among species, with MICs ranging from 8-64 μg/mL. After exposure of the C. albicans strains to curcumin, it was observed a decrease in the number of viable cells and damage to cell membranes, the mitochondrial function of C. albicans cells appears to be affected after exposure to curcumin. O...
Ibuprofen antifungal activity on both planktonic and biofilm forms of fluconazo...
Sampaio, Letícia S.; Silva, Cecília R. da; Campos, Rosana S.; Nascimento, Francisca Bruna Stefany Aires do; Andrade Neto, João Batista deOver the past few decades, researches have reported an increased incidence of invasive candidiasis and suggested that the majority of infections produced by this pathogen are associated with biofilm growth, which are more resistant to antimicrobial agents than planktonic cells. In addition to these problems, there are few antifungal agents available and it is necessary the development of novel therapeutic strat...
Accuracy of buffy coat in the diagnosis of disseminated histoplasmosis in AIDS-...
Leitão, Terezinha do Menino Jesus Silva; Oliveira Filho, Antonio M. P.; Sousa Filho, José Evaldo P.; Tavares, Bruno M.; Mesquita, Jacó R. L.The bu y coat is obtained routinely for disseminated histoplamosis (DH) diagnosis in Ceará, Brazil. The aim of this study is to describe the accuracy of staining smears for Histoplasma in the bu y coat of AIDS-patients with DH. From 2012–2013, all results of stained bu y coat smears and culture for fungi performed at São José Hospital were recorded. In total, 489 bu y coats of 361 patients were studied; 19/361 ...