3 documents found, page 1 of 1
Single nucleotide polymorphisms of the genes IL-2, IL-2RB, and JAK3 in patients...
Araújo Santos, Felipe Jules de; Silva, Lener Santos da; Santo, José do Espírito; Mesquita, Tirza Gabrielle Ramos de; Souza, Mara Lúcia Gomes deLeishmaniasis is a disease caused by intracellular protozoan parasites of the genus Leishmania. In endemic areas, only a portion of exposed subjects develops cutaneous leishmaniasis (CL), suggesting that the genetic inheritance of the host plays a vital role in both resistance and susceptibility to the disease. Interleukin-2 (IL-2) is a cytokine that plays a central role in the regulation of the immune response...
Analysis of the immunological biomarker profile during acute zika virus infecti...
Naveca, Felipe Gomes; Pontes, Gemilson Soares; Chang, Aileen Yu Hen; Silva, George Allan Villarouco da; Nascimento, Valdinete Alves doBACKGROUND Infection with Zika virus (ZIKV) manifests in a broad spectrum of disease ranging from mild illness to severe neurological complications and little is known about Zika immunopathogenesis. OBJECTIVES To define the immunologic biomarkers that correlate with acute ZIKV infection. METHODS We characterized the levels of circulating cytokines, chemokines, and growth factors in 54 infected patients of both ...
Use of recombinant antigens for sensitive serodiagnosis of american tegumentary...
Sato, Camila Massae; Sanchez, Maria Carmen Arroyo; Celeste, Beatriz Julieta; Duthie, Malcolm S; Guderian, Jeffrey; Reed, Steven GThis work was supported by Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo (grant 2015/22075-8 and fellowship 2016/02622-7 to C.M.S.), by CAPES (fellowship to C.M.S.), by Conselho Nacional de Pesquisa (research fellowship to H.G.), and by Laborat?rios de Investiga??o M?dica (LIM-38-HC, FMUSP). This research was also supported by funding from the Bill and Melinda Gates Foundation under grants OPP49932 and O...