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The influence of metabolic syndrome in the outcomes of colorectal cancer patients

Goulart, A; Varejão, A; Nogueira, F; Martins, S; Mesquita-Rodrigues, A; Sousa, N; Leão, P

AIMS: Determine the influence of metabolic syndrome and its different components in the outcomes of colorectal cancer surgery at 30days. MATERIALS AND METHODS: Prospective study that included all patients submitted to elective colorectal cancer surgery between August 2015 and August 2016 at Hospital de Braga. Clinical and laboratory parameters evaluated pre-operatively were: central obesity, blood pressure, fas...


Ki-67 Expression in CRC Lymph Node Metastasis Does Not Predict Survival

Martins, SF; Amorim, R; Mota, SC; Costa, L; Pardal, F; Mesquita-Rodrigues, A; Longatto-Filho, A

Colorectal cancer is one of the most common malignancies and a leading cause of cancer death worldwide. Molecular markers may improve clinicopathologic staging and provide a basis to guide novel therapeutic strategies which target specific tumour-associated molecules according to individual tumour biology; however, so far, no ideal molecular marker has been found to predict disease progression. We tested Ki-67 ...


Ki-67 Expression in CRC Lymph Node Metastasis Does Not Predict Survival

Martins, SF; Amorim, R; Coelho-Mota, S; Costa, L; Pardal, F; Mesquita-Rodrigues, A; Longatto-Filho, A

Colorectal cancer is one of the most common malignancies and a leading cause of cancer death worldwide. Molecular markers may improve clinicopathologic staging and provide a basis to guide novel therapeutic strategies which target specific tumour-associated molecules according to individual tumour biology; however, so far, no ideal molecular marker has been found to predict disease progression. We tested Ki-67 ...


Clinicopathological correlation and prognostic significance of VEGF-A, VEGF-C, ...

Martins, SF; Garcia, EA; Luz, MA; Pardal, F; Mesquita-Rodrigues, A; Filho, AL

BACKGROUND: Colorectal cancer (CRC) is the third most common type of cancer and the fourth most frequent cause of cancer death. Literature indicates that vascular endothelial growth factor is a predominant angiogenic factor and that angiogenesis plays an important role in the progression of CRC. PATIENTS AND METHODS: The present series consisted of tissue samples obtained from 672 patients who had undergone lar...


Cirurgia Colorrectal Laparoscópica: A experiência de uma unidade de coloproctol...

Ribas, S; Leão, P; Pereira, R; Rosa, N; Martins, S; Lamelas, J; Mesquita-Rodrigues, A


Role of endoglin and VEGF family expression in colorectal cancer prognosis and ...

Martins, SF; Reis, RM; Mesquita-Rodrigues, A; Baltazar, F; Filho, AL

Colorectal cancer (CRC) is one of the cancer models and most of the carcinogenic steps are presently well understood. Therefore, successful preventive measures are currently used in medical practice. However, CRC is still an important public health problem as it is the third most common cancer and the fourth most frequent cause of cancer death worldwide. Nowadays, pathologic stage is a unique and well-recognize...


Tumor de Krukenberg: A propósito de um caso clínico

Ribas, S; Campelos, S; Lamelas, J; Mesquita-Rodrigues, A


Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal ...

Pinheiro, C; Longatto-Filho, A; Scapulatempo, C; Mesquita-Rodrigues, A; Alves, VA; Schmitt, F; Baltazar, F

Tumour cells are known to be highly glycolytic, thus producing high amounts of lactic acid. Monocarboxylate transporters (MCTs), by promoting the efflux of the accumulating acids, constitute one of the most important mechanisms in the maintenance of tumour intracellular pH. Since data concerning MCT expression in colorectal carcinomas (CRC) are scarce and controversial, the present study aimed to assess the exp...


Twenty-four Hours Evaluation After Ambulatory Surgery: Retrospective Review

Leão, P; Braga dos Anjos, JM; Vicente, L; Faria, T; Mesquita-Rodrigues, A; Gomes, A


Lipossarcoma Retroperitoneal

Leão, P; Martins, S; Vilaça, S; Lamelas, J; Falcão, J; Mesquita-Rodrigues, A


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