4 documents found, page 1 of 1
Absence of CCR5 increases neutrophil recruitment in severe herpetic encephalitis
Vilela, Márcia Carvalho; Lima, Graciela Kunrath; Rodrigues, David Henrique; Lacerda-Queiroz, Norinne; Pedroso, Vinicius Sousa PietraThe neuroinflammatory response aimed at clearance of herpes simplex virus-1 (HSV-1) plays a key role in the pathogenesis of neuroaxonal damage in herpetic encephalitis. Leukocytes activated in an adaptive immune response access brain tissue by passing through the blood–brain barrier. The chemokine CCL5/RANTES is involved in recruitment of these cells to the brain acting via the receptors CCR1, CCR3 and mainly C...
Protective Immunity and Safety of a Genetically Modified Influenza Virus Vaccine
Barbosa, Rafael Polidoro Alves; Salgado, Ana Paula Carneiro; Garcia, Cristiana Couto; Galvao Filho, Bruno; Gonçalves, Ana Paula de FariaFundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Laboratorio de Imunopatologia. Belo Horizonte, MG, Brasil/Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Laboratório de Imunoparasitologia, Departamento de Bioquímica e Imunologia. Belo Horizonte, MG, Brasil.; Fundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Laboratório de Imunopatologia. Belo Horizonte, MG, Brasil.; Univers...
Mast cell concentration and skin wound contraction in rats treated with Brazili...
Estevão, Lígia Reis Moura; Medeiros, Juliana Pinto De; Simões, Ricardo Santos; Arantes, Rosa Maria Esteves; Rachid, Milene AlvarengaMade available in DSpace on 2015-08-21T17:54:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-04-01. Added 1 bitstream(s) on 2015-08-24T14:42:07Z : No. of bitstreams: 1 S0102-86502015000400289.pdf: 668960 bytes, checksum: 9c4cbd8871fd8362e8521af011cdceed (MD5); PURPOSE: To evaluate wound contraction and the concentration of mast cells in skin wounds treated with 5% BPT essential oil-based ointment in r...
Blockade of CXCR1/2 chemokine receptors protects against brain damage in ischem...
Sousa, Larissa Fonseca da Cunha; Coelho, Fernanda Matos; Rodrigues, David Henrique; Campos, Alline Cristina; Barcelos, Luciola da SilvaOBJECTIVE: Ischemic stroke may result from transient or permanent reductions of regional cerebral blood flow. Polymorphonuclear neutrophils have been described as the earliest inflammatory cells to arrive in ischemic tissue. CXCR1/2 receptors are involved in the recruitment of these cells. However, the contribution of these chemokine receptors during transient brain ischemia in mice remains poorly understood. I...