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Microfluidics Integration into Low-Noise Multi-Electrode Arrays

Ribeiro, Mafalda; Ali, Pamela; Metcalfe, Benjamin; Moschou, Despina; Rocha, Paulo R. F.

Organ-on-Chip technology is commonly used as a tool to replace animal testing in drug development. Cells or tissues are cultured on a microchip to replicate organ-level functions, where measurements of the electrical activity can be taken to understand how the cell populations react to different drugs. Microfluidic structures are integrated in these devices to replicate more closely an in vivo microenvironment....


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