10 documents found, page 1 of 1
A scoping review of the assessment reports of genetic or genomic tests reveals ...
Pezzullo, Angelo Maria; Gris, Angelica Valz; Scarsi, Nicolò; Tona, Diego Maria; Porcelli, Martina; Di Pumpo, Matteo; Piko, Peter; Adany, RozaObjectives: Genetic and genomic tests are the cornerstone of personalized preventive approaches. Inconsistency in evaluating their clinical utility is often cited as a reason for their limited implementation in clinical practice. Previous reviews have primarily focused on theoretical frameworks used for clinical utility evaluations of genetic tests, rather than actual assessments and examined dimensions, rather...
The PROPHET project paves the way for personalized prevention in the future hea...
Pastorino, Roberta; Pezzullo, Angelo Maria; Osti, Tommaso; Adany, Roza; Borry, Pascal; Barnhoorn, Floris; Fadil, Eva; Kroese, Mark; Metspalu, AndresNo abstract available
Heterogeneous contributions of change in population distribution of body mass i...
Iurilli, Maria L. C.; Zhou, Bin; Bennett, James E.; Carrillo-Larco, Rodrigo M.; Sophiea, Marisa K.; Rodriguez-Martinez, Andrea; Bixby, HonorMade available in DSpace on 2022-04-28T19:30:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-01; From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of ...
Worldwide trends in hypertension prevalence and progress in treatment and contr...
Zhou, Bin; Carrillo-Larco, Rodrigo M.; Danaei, Goodarz; Riley, Leanne M.; Paciorek, Christopher J.; Stevens, Gretchen A.; Gregg, Edward W.Made available in DSpace on 2022-04-28T17:23:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-11; WHO; Abdul Latif Jameel Institute for Disease and Emergency Analytics - Community Jameel, at Imperial College London, London, UK; British Heart Foundation (Centre of Research Excellence); Background Hypertension can be detected at the primary health-care level and low-cost treatments can effectively con...
Heterogeneous contributions of change in population distribution of body mass i...
Iurilli, Maria L. C.; Zhou, Bin; Bennett, James E.; Carrillo-Larco, Rodrigo M.; Sophiea, Marisa K.; Rodriguez-Martinez, Andrea; Bixby, HonorMade available in DSpace on 2021-06-25T15:08:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-09; Wellcome Trust; From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in th...
Worldwide trends in body-mass index, underweight, overweight, and obesity from ...
Ezzati, Majid; Bentham, James; Di Cesare, Mariachiara; Bilano, Ver; Bixby, Honor; Zhou, Bin; Stevens, Gretchen A.; Riley, Leanne M.; Taddei, CristinaMade available in DSpace on 2018-11-26T20:04:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-12-16; Wellcome Trust; AstraZeneca; Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cove...
Contributions of mean and shape of blood pressure distribution to worldwide tre...
Zhou, Bin; Bentham, James; Di Cesare, Mariachiara; Bixby, Honor; Danaei, Goodarz; Hajifathalian, Kaveh; Taddei, Cristina; Carrillo-Larco, Rodrigo M.Made available in DSpace on 2018-11-26T22:38:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-06-01; Wellcome Trust; Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successfu...
Analysis of shared heritability in common disorders of the brain
Anttila, Verneri; Bulik-Sullivan, Brendan; Finucane, Hilary K.; Walters, Raymond K.; Bras, Jose; Duncan, Laramie; Escott-Price, ValentinaDisorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We quantified the genetic sharing of 25 brain disorders from genome-wide association studies of 265,218 patients and 784,643 control participants and assessed their relationship to 17 phenotypes from 1,191,588 individuals. Psychiatric disorders share common varian...
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479...
Zhou, Bin; Bentham, James; Di Cesare, Mariachiara; Bixby, Honor; Danaei, Goodarz; Cowan, Melanie J; Paciorek, Christopher J; Singh, GitanjaliBackground Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. Methods For this analysis, we poo...
Worldwide trends in body-mass index, underweight, overweight, and obesity from ...
Abarca-Gómez, Leandra; Abdeen, Ziad A~.; Hamid, Zargar Abdul; Abu-Rmeileh, Niveen M.; Acosta-Cazares, Benjamin; Acuin, Cecilia; Adams, Robert J.Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. Methods We pooled 2416 population-based s...