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The influence of temperature on the impacts of caffeine in mussels: evaluating ...

Cunha, Marta; Petrillo, Vincenzo; Madeira, Madalena; He, Yide; Coppola, Francesca; Meucci, Valentina; De Marchi, Lucia; Soares, Amadeu M. V. M.

In aquatic ecosystems, the presence of pharmaceuticals, particularly caffeine (CAF), has been linked to wastewater discharge, hospital waste, and the disposal of expired pharmaceutical products containing CAF. Additionally, rising temperatures due to climate change are anticipated in aquatic environments. This study aimed to assess the toxicity of various CAF concentrations under current (17 °C) and projected (...


Exploring toxicological interactions in a changing sea: the case of the alkaloi...

Russo, Tania; Coppola, Francesca; Paris, Debora; De Marchi, Lucia; Meucci, Valentina; Motta, Andrea; Carbone, Marianna; Di Cosmo, Anna

The bisindolic alkaloid caulerpin (CAU) is a bioactive compound isolated from green algae of the genus Caulerpa that are highly invasive in the Mediterranean Sea. On the other side, the purine alkaloid caffeine (CAF) is one of the most globally consumed psychoactive substances and a widespread anthropogenic water pollutant. Both compounds display a large panel of biological properties and are well known to accu...


Combined effects of temperature rise and sodium lauryl sulfate in the Mediterra...

Freitas, Rosa; Arrigo, Federica; Coppola, Francesca; Meucci, Valentina; Battaglia, Federica; Soares, Amadeu M V M; Pretti, Carlo; Faggio, Caterina

Personal care products (PCPs) are those compounds used daily (e.g., soaps, shampoos, deodorants, and toothpaste), explaining their frequent detection in aquatic systems. Still, scarce information is available on their effects on inhabiting wildlife. Among the most commonly used PCPs is the surfactant Sodium Lauryl Sulfate (SLS). The present study investigated the influence of temperature (CTL 17 ºC vs 22 ºC) on...


Sub-lethal effects induced in Mytilus galloprovincialis after short-term exposu...

Paciello, Sofia; Russo, Tania; De Marchi, Lucia; Soares, Amadeu M. V. M.; Meucci, Valentina; Pretti, Carlo; He, Yide; Della Torre, Camila; Freitas, Rosa

Surfactants are among the most common PPCPs that reach coastal systems, being often used in large quantities in cleaning products such as detergents and soap powders. Sodium lauryl sulfate (SLS) is listed in this group of emerging contaminants. Previous studies have already demonstrated the presence of SLS in aquatic environments and the negative effects on organisms living there. However, with ocean acidificat...


The influence of salinity on sodium lauryl sulfate toxicity in Mytilus gallopro...

Freitas, Rosa; Coppola, Francesca; Meucci, Valentina; Battaglia, Federica; Soares, Amadeu M. V. M.; Pretti, Carlo; Faggio, Caterina

The influence of salinity on the effects of sodium lauryl sulfate (SLS) was evaluated using the Mediterranean mussel Mytilus galloprovincialis, exposed for 28 days to SLS (control-0.0 and 4.0 mg/L) under three salinity levels (Control-30, 25 and 35). The effects were monitored using biomarkers related to metabolism and energy reserves, defence mechanisms (antioxidant and biotransformation enzymes) and cellular ...


The influence of climate change related factors on the response of two clam spe...

Costa, Silvana; Coppola, Francesca; Pretti, Carlo; Intorre, Luigi; Meucci, Valentina; Soares, Amadeu M. V. M.; Freitas, Rosa; Solé, Montserrat

Diclofenac (DIC) is one of the non-steroidal anti-inflammatory drugs (NSAID) with higher consumption rates, used in both human and veterinary medicine. Previous studies already demonstrated the presence of this drug in aquatic environments and adverse effects towards inhabiting organisms. However, with the predictions of ocean acidification and warming, the impacts induced by DIC may differ from what is present...


Toxic impacts induced by Sodium lauryl sulfate in Mytilus galloprovincialis

Freitas, Rosa; Silvestro, Serena; Coppola, Francesca; Costa, Silvana; Meucci, Valentina; Battaglia, Federica; Intorre, Luigi; Soares, Amadeu M. V. M.

Pharmaceuticals and personal care products (PPCPs) are continuously dispersed into the environment, as a result of human and veterinary use, reaching aquatic coastal systems and inhabiting organisms. However, information regarding to toxic effects of these compounds towards marine invertebrates is still scarce, especially in what regards to metabolic capacity and oxidative status alterations induced in bivalves...


Combined effects of salinity changes and salicylic acid exposure in Mytilus gal...

Freitas, Rosa; Silvestro, Serena; Coppola, Francesca; Meucci, Valentina; Battaglia, Federica; Intorre, Luigi; Soares, Amadeu M. V. M.; Pretti, Carlo

Pharmaceuticals and Personal care products (PPCPs) are frequently released into several marine matrices, representing significant environmental and ecotoxicological risks. Among the widest spread PPCPs in aquatic systems is Salicylic acid (SA), with known negative effects on marine and freshwater species. Nevertheless, the toxicity resulting from these emerging pollutants, including SA, together with climate ch...


The influence of temperature on the effects induced by Triclosan and Diclofenac...

Freitas, Rosa; Coppola, Francesca; Costa, Silvana; Pretti, Carlo; Intorre, Luigi; Meucci, Valentina; Soares, Amadeu M. V. M.; Solé, Montserrat

Little is known about the consequences of exposure to pharmaceuticals and personal care products (PPCPs) in elevated temperatures associated with climate change. To increase the knowledge on this topic, Mytilus galloprovincialis mussels were exposed to 1.0 µg/L of either the antimicrobial Triclosan (TCS) or the pharmaceutical drug Diclofenac (DIC), at control (17ºC) and 4ºC raised (21ºC) temperatures for 28 day...


Does salinity modulates the response of Mytilus galloprovincialis exposed to tr...

Freitas, Rosa; Coppola, Francesca; Costa, Silvana; Manzini, Chiara; Intorre, Luigi; Meucci, Valentina; Soares, Amadeu M. V. M.; Pretti, Carlo

In the present study Mytilus galloprovincialis mussels were exposed for 28 days to three salinities: 30 (control), 25 and 35. Simultaneously, organisms at each salinity were exposed to either the antimicrobial agent Triclosan (TCS) or the pharmaceutical drug Diclofenac (DIC) at 1 μg/L. Salinity alone and exposure to PPCPs changed mussel's metabolic capacity and oxidative status, but no additive or synergetic ef...


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