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ZIKV Strains Elicit Different Inflammatory and Anti-Viral Responses in Microgli...

Oliveira, Fernanda Bellaniza Caminha de; Freire, Vanessa Paola Alves Sampaio de Sá; Coelho, Sharton Vinicius Antunes; Meuren, Lana Monteiro

In recent years, the Zika Virus (ZIKV) has caused pandemic outbreaks associated with a high rate of congenital ZIKV syndrome (CZS). Although all strains associated with worldwide outbreaks derive from the Asian lineage, the reasons for their enhanced spread and severity are not fully understood. In this study, we conducted a comparative analysis of miRNAs (miRNA-155/146a/124) and their cellular targets (SOCS1/3...


Viral immunogenicity determines epidemiological fitness in a cohort of DENV-1 i...

Pinheiro, Tauyne Menegaldo; Oliveira Mota, Manlio Tasso de; Aranha Watanabe, Aripuana Sakurada; Biselli-Perico, Joice Matos [UNESP]

Made available in DSpace on 2018-11-26T17:51:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-05-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); NIH/NIAID; The dynamics of dengue virus (DENV) circulation depends on serotype, genotype and lineage replacement and turnover. In Sao Jose do Rio Preto, Brazil, we observe...

Date: 2018   |   Origin: Oasisbr

Zika-virus-infected human full-term placental explants display pro-inflammatory...

Ribeiro, Milene Rocha [UNESP]; Moreli, Jusciele Brogin; Marques, Rafael Elias; Papa, Michelle Premazzi; Meuren, Lana Monteiro; Rahal, Paula [UNESP]

Made available in DSpace on 2018-12-11T17:20:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-10-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Zika virus (ZIKV) is a flavivirus that has been highly correlated with the development of neurological disorders and other malformations in newborns and stillborn fetuses after congenital infection. This association is supported by the prese...

Date: 2018   |   Origin: Oasisbr

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