In recent years, the Zika Virus (ZIKV) has caused pandemic outbreaks associated with a high rate of congenital ZIKV syndrome (CZS). Although all strains associated with worldwide outbreaks derive from the Asian lineage, the reasons for their enhanced spread and severity are not fully understood. In this study, we conducted a comparative analysis of miRNAs (miRNA-155/146a/124) and their cellular targets (SOCS1/3...
Made available in DSpace on 2018-11-26T17:51:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-05-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); NIH/NIAID; The dynamics of dengue virus (DENV) circulation depends on serotype, genotype and lineage replacement and turnover. In Sao Jose do Rio Preto, Brazil, we observe...
Made available in DSpace on 2018-12-11T17:20:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-10-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Zika virus (ZIKV) is a flavivirus that has been highly correlated with the development of neurological disorders and other malformations in newborns and stillborn fetuses after congenital infection. This association is supported by the prese...