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A study of the mechanism of the release of ATP from rat cortical astroglial cel...

Queiroz, G; Meyer, DK; Meyer, A; Starke, K; von Kugelgen, I

Glutamate and the selective agonists at ionotropic glutamate receptors N-methyl-D-aspartate, alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) and kainate release ATP from superfused primary cultures of rat cortical astrocytes. The mechanism of this release was investigated. The release of ATP elicited by N-methyl-D-aspartate and kainate was abolished or greatly reduced in the absence of external calc...

Date: 1999   |   Origin: Repositório Aberto da Universidade do Porto
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