3 documents found, page 1 of 1
Incidence and outcomes of acute kidney injury following orthotopic lung transpl...
Fidalgo, P; Ahmed, M; Meyer, S; Lien, D; Weinkauf, J; Cardoso, F; Jackson, K; Bagshaw, SBACKGROUND:Acute kidney injury (AKI) is a serious complication following lung transplantation (LTx). We aimed to describe the incidence and outcomes associated with AKI following LTx. METHODS: A retrospective population-based cohort study of all adult recipients of LTx at the University of Alberta between 1990 and 2011. The primary outcome was AKI, defined and classified according to the Kidney Disease: Improvi...
Recurrence After Operative Management of Intrahepatic Cholangiocarcinoma
Hyder, O; Hatzaras, I; Sotiropoulos, G; Paul, A; Alexandrescu, S; Marques, H; Pulitano, C; Barroso, E; Clary, B; Aldrighetti, L; Ferrone, C; Zhu, AINTRODUCTION: Data on recurrence after operation for intrahepatic cholangiocarcinoma (ICC) are limited. We sought to investigate rates and patterns of recurrence in patients after operative intervention for ICC. METHODS: We identified 301 patients who underwent operation for ICC between 1990 and 2011 from an international, multi-institutional database. Clinicopathologic data, recurrence patterns, and recurrence...
Mutations in CTC1, Encoding Conserved Telomere Maintenance Component 1, Cause C...
Anderson, B; Kasher, P; Mayer, J; Szynkiewicz, M; Jenkinson, E; Bhaskar, S; Urquhart, J; Daly, S; Dickerson, J; O'Sullivan, J; Leibundgut, E; Muter, JCoats plus is a highly pleiotropic disorder particularly affecting the eye, brain, bone and gastrointestinal tract. Here, we show that Coats plus results from mutations in CTC1, encoding conserved telomere maintenance component 1, a member of the mammalian homolog of the yeast heterotrimeric CST telomeric capping complex. Consistent with the observation of shortened telomeres in an Arabidopsis CTC1 mutant and t...