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Rapid FTIR Spectral Fingerprinting of Kidney Allograft Perfusion Fluids Disting...

Ramalhete, Luís; Araújo, Rúben; Bigotte Vieira, Miguel; Vigia, Emanuel; Pena, Ana; Carrelha, Sofia; Ferreira, Anibal; Calado, Cecília R.C.

Funding Information: This research was funded by Centro Cl\u00EDnico Acad\u00E9mico de Lisboa, grant number FF-CCAL.05.2025. Publisher Copyright: © 2025 by the authors.; Background/Objectives: Rapid, objective phenotyping of donor kidneys is needed to support peri-implant decisions. Label-free Fourier-transform infrared (FTIR) spectroscopy of static cold-storage Celsior® perfusion fluid can discriminate kidneys...


Pancreas Rejection in the Artificial Intelligence Era

Vigia, Emanuel; Ramalhete, Luís; Ribeiro, Rita; Barros, Inês; Chumbinho, Beatriz; Filipe, Edite; Pena, Ana; Bicho, Luís; Nobre, Ana; Carrelha, Sofia

Introduction: Pancreas transplantation is currently the only treatment that can re-establish normal endocrine pancreatic function. Despite all efforts, pancreas allograft survival and rejection remain major clinical problems. The purpose of this study was to identify features that could signal patients at risk of pancreas allograft rejection. Methods: We collected 74 features from 79 patients who underwent simu...


The Impact of Donor Risk Index, Recipients' and Operative Characteristics on Po...

Cardoso, Filipe S.; Bagulho, Luis; Coelho, João S.; Lamelas, Jorge; Mateus, Élia; Mendes, Milena; Glória, Helena; Ribeiro, Vasco; Mega, Raquel

Publisher Copyright: © 2022; Background and Aims: The donor risk index (DRI) quantifies donor-related characteristics potentially associated with increased risk of early graft failure. We aimed to assess the impact of the DRI, recipient and perioperative factors on post liver transplant (LT) outcomes. Methods: This was a single-center retrospective cohort study including all adult (≥18 years) patients who under...


Combined lung-kidney transplantation

Silva, David T.; Dantas, Carolina; Santos, Ana Sofia; Remédio, Francisco; Pena, Ana; Calvinho, Paulo; Semedo, Luísa; Cardoso, João; Nolasco, Fernando

A significant dysfunction of another organ is usually considered an absolute contraindication for lung transplantation, unless multiorgan transplantation is indicated and practical, as is the case of combined lung-kidney transplantation. Few cases of combined lung-kidney transplantation have been described in the literature; however, it is known that, in certain cases, it is the only way to offer an opportunity...


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