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Development of a decellularized extracelular matrix from porcine aorta for hear...

Reis, Mariana S.; Rosadas, Marta; Ho, Chou I.; Sousa, Teresa; Pazmino, Carlos; Costa, João; Vervenne, Thibault; Oliveira, Ana L.; Ribeiro, Viviana P.

Cardiovascular diseases are the leading cause of adult mortality worldwide, according to the World Health Organization [1]. An important surgical approach for treating diseased aortic valves is the Ross procedure, in whic the affected aortic valve is replaced with an autograft from the patient’s own pulmonary valve.


Development of a decellularized extracelular matrix from porcine aorta for hear...

Reis, Mariana S.; Rosadas, Marta; Ho, Chou I.; Costa, João; Vervenne, Thibault; Oliveira, Ana L.; Ribeiro, Viviana P.; Mignon, Arn

Cardiovascular diseases are the leading cause of adult mortality worldwide, according to the WHO [1]. An important surgical approach for treating diseased aortic valves is the Ross procedure, in which the affected aortic valve is replaced with an autograft from the patient’s own pulmonary valve. The main concern about this procedure is linked to wall dilatation, which can lead to valve leakage and reoperation. ...


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