5 documents found, page 1 of 1
Selective Digestive Decontamination in Hemato-Oncological Patients Colonized wi...
de Abreu Luís, Sara; Mimoso Santos, CarlaInfections caused by multidrug-resistant Gram-negative bacteria, including carbapenem-resistant Enterobacterales, are a global threat and their gradual increase is alarming. They represent a major challenge to public health because of limited therapeutic options and high case-fatality rates. Hemato-oncological patients represent a high-risk subpopulation for these types of infections, more specifically in previ...
Extensively drug-resistant Pseudomonas aeruginosa: clinical features and treatm...
Pedro, Diogo; Paulo, Sérgio; Mimoso Santos, Carla; Fonseca, Ana Bruschy; Cristino, José Melo; Ayres Pereira, Álvaro; Caneiras, CatiaIntroduction: Extensively drug-resistant Pseudomonas aeruginosa (XDR-PA) is a growing concern due to its increasing incidence, limited therapeutic options, limited data on the optimal treatment, and high mortality rates. The study aimed to characterize the population, the outcome and the microbiological characteristics of XDR-PA identified in a Portuguese university hospital center. Methods: All XDR-PA isolates...
Vascular graft infections in open aortic surgery: who is at risk and how to tre...
Duarte, Antonio; Mendes Pedro, Diogo; Gouveia e Melo, Ryan; Martins, Beatriz; Mimoso Santos, Carla; Sobrinho, Gonçalo; Fernandes e Fernandes, RuyINTRODUCTION: Vascular graft infections are a rare and severe complication of open aortic surgery. As such, strategies to improve diagnosis and management are paramount. Nevertheless, there is little evidence regarding the factors associated with a higher susceptibility of infection. Moreover, there is little consensus on the best diagnostic workup and most adequate approaches to control and mitigate this surgi...
Microbial evolution of vascular graft infections in a tertiary hospital based o...
Melo, Ryan; Martins, Beatriz; Pedro, Diogo Mendes; Mimoso Santos, Carla; Duarte, António; Fernandes E Fernandes, Ruy; Garrido, Pedro; Pedro, Luís MBackground: Vascular graft infections are a serious complication in vascular surgery. Correct antibiotic therapy targeted to the most likely infecting species is essential to treat these patients, although the bacterial epidemiology and pathogenesis are still not completely understood. We analyzed the behavior of vascular graft infections and the microbiologic patterns of resistance. Methods: A 10-year (2008-20...
Evolving epidemiology of carbapenemase-producing Enterobacteriaceae in Portugal...
Pires, Daniela; Zagalo, Alexandra; Mimoso Santos, Carla; Cota de Medeiros, F.; Duarte, Aida; Lito, Luís Marques; Cristino, José MeloDespite great efforts to enhance European epidemiological surveillance on carbapenemase-producing Enterobacteriaceae (CPE), information from several countries remains scarce. To address CPE epidemiology in Portugal, we have undertaken a retrospective cohort study of adults with CPE cultures identified in the microbiology laboratory of a tertiary hospital, in 2012. Sixty patients from 25 wards or intensive care ...