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Real-world effectiveness in hypertension and hyperlipidemia collaborative manag...

Costa, Suzete; Biscaia, José Luís; Horta, Maria Rute; Romano, Sónia; Guerreiro, José; Heudtlass, Peter; Cary, Maria; Romão, Mariana

Funding Information: This trial was promoted by the Agrupamento dos Centros de Saúde (ACeS) (NHS Group of Primary Care Units) of the Baixo Mondego Region and the Associação Nacional das Farmácias (ANF) (Portuguese National Association of Pharmacies) and was funded by the ANF. Hartmann supplied blood pressure monitors to intervention pharmacies. Trial Registration Number: ISRCTN13410498. S.C. paid for the open-a...


Real-world effectiveness of palbociclib plus fulvestrant in advanced breast cancer

Cardoso Borges, Fábio; Alves da Costa, Filipa; Ramos, Adriana; Ramos, Catarina; Bernardo, Catarina; Brito, Cláudia; Mayer-da-Silva, Alexandra

Funding Information: We have read the journal's policy and the authors of this manuscript have the following competing interests: ARF reports travel grants from Roche and advisory board fees from Daiichi Sankyo, Gilead, Merck Sharp & Dohme, Novartis and Roche, outside the submitted work. DMB reports travel grants from LEO Farmacêuticos, Merck Sharp & Dohme, Ipsen, Janssen, Roche, and Novartis, advisory board fe...


Detailing the epidemiological and clinical characteristics of chronic lymphocyt...

Borges, Fábio Cardoso; Ramos, Adriana; Lourenço, António; da Silva, Maria Gomes; Miranda, Ana

Publisher Copyright: © 2021 Cardoso Borges et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.; Background Chronic lymphocytic leukaemia (CLL) is the most common leukaemia among adults in western countries. Considering the ...


Vitamin D-related polymorphisms and vitamin D levels as risk biomarkers of COVI...

Freitas, Ana Teresa; Calhau, Conceição; Antunes, Gonçalo; Araújo, Beatriz; Bandeira, Matilde; Barreira, Sofia; Bazenga, Filipa; Braz, Sandra

Funding Information: We thank all the study participants, who donated blood and authorized the genetic analysis and the collection of the clinical and phenotypic personal data. This project was supported by the “Fundação para a Ciência e Tecnologia”, program “Research 4 Covid-19 Apoio especial a projetos de implementação rápida para soluções inovadoras de resposta à pandemia de COVID-19”. It was also partially ...


International consensus on antinuclear antibody em Portugal

Sousa, Maria José; Neves, Esmeralda; Figueiras, Otília; Cruz, Ana Paula; Fernandes, Isabel; Mendes, Alexandra; Santos, Maria do Céu; Cunha, Rosário

Introduction: Screening for autoantibodies in HEp-2 cells by indirect immunofluorescence is currently accepted as the gold-standard test for the diagnosis of systemic autoimmune diseases. The main objective of the International Consensus on ANA Patterns is to achieve a consensus on the nomenclature and description of antinuclear antibody morphological patterns. This work aims to build on the International Conse...


Low persistence with oral biphosphonate treatment in postmenopausal osteoporosis

Torre, Carla; Guerreiro, José; Mendes, Zilda; Miranda, Ana; Bragança, Fátima; Cristino, Joaquim; Canhão, Helena; Branco, Jaime

BACKGROUND: Osteoporotic fractures are a major cause of morbidity and mortality. It is recognized that persistence with medication is crucial to reach optimal clinical outcomes. We aimed to estimate the persistence level to weekly and monthly oral bisphosphonates (OBP) in women with postmenopausal osteoporosis (PMO) over 24 months from therapy initiation in a population-based setting. METHODS: Prospective obser...


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