9 documents found, page 1 of 1
Chronic hepatitis C treatment in HIV co-infection in Portugal: Results from a c...
Miranda, AC; Mendez J, J; Serrão, R; Vale, F; Manata, MJ; Pinto, S; Gomes, A; Valente, C; Pacheco, P, et al.Direct-acting antiviral drugs (DAAs) have recently changed the paradigm of hepatitis C therapy, significantly improving treatment response rates, patient life expectancy and quality of life. In Portugal, sofosbuvir (SOF) and SOF/ledipasvir (SOF/LDV) were fully reimbursed by the National Health System since early 2015 and generalized use of interferon-free DAA based regimens became current practice. During 2016,...
Chronic Hepatitis C Treatment in HIV Co-Infection in Portugal: Results from a C...
Miranda, AC; Mendez, J; Serrão, R; Vale, F; Manata, MJ; Pinto, S; Gomes, A; Valente, C; Pacheco, P; Pazos, R; Pereira, R; Martins, A; Germano, IDirect-acting antiviral drugs (DAAs) have recently changed the paradigm of hepatitis C therapy, significantly improving treatment response rates, patient life expectancy and quality of life. In Portugal, sofosbuvir (SOF) and SOF/ledipasvir (SOF/LDV) were fully reimbursed by the National Health System since early 2015 and generalized use of interferon-free DAA based regimens became current practice. During 2016,...
Perfil Terapêutico da Hipertensão da Rede de Médicos Sentinela
Martins, AP; Melo, M; Mendes, Z; Ferreira, AP; Miranda, AC; Falcão, IM; Domingues, JC; Goucha, PObjectivosDescrever o perfil terapêutico da hipertensão na Rede de Médicos Sentinela e analisar o padrão de prescrição dos anti-hipertensores de acordo com a forma de hipertensão e co-morbilidades. Tipo de estudoEstudo transversal LocalRede de Médicos-Sentinela de Portugal População Doentes hipertensos que se deslocaram á consulta entre 15 de Setembro e 30 de Outubro de 1998, à excepção de doentes menores de 18...
Self-medication in a Portuguese Urban Population: A Prevalence Study
Martins, AP; Miranda, AC; Mendes, Z; Soares, MA; Ferreira, AP; Nogueira, A; Soares, MAPurposeTo determine the prevalence of self-medication in a Portuguese urban population. To assess the feasibility of performing these studies in community pharmacies. Methods A cross-sectional study was chosen to collect information about demography, use of health services and drug utilization in a sample of pharmacy user-purchasers in a pre-determined period of time. ResultsThe proportion of pharmacies which p...
Effect of Reminder Cards on Compliance with Antihypertensive Medication
Costa, F; Guerreiro, JP; Melo, M; Miranda, AC; Martins, AP; Garção, J; Madureira, BObjectivePoor compliance to antihypertensive medications has been identified as a primary cause of uncontrolled blood pressure (BP), with consequent increases in hypertension-related morbidity and mortality. Therefore, any measure known to improve compliance should be encouraged. This study assessed the impact of reminder cards on compliance to antihypertensive therapy. MethodA field trial was undertaken in pha...
Effectiveness of a Collaborative Care Intervention Between Pharmacies and Prima...
Costa, S; Rodrigues, AT; Biscaia, JS; Romano, S; Guerreiro, JP; Heudtlass, P; Cary, M; Romão, M; Rodrigues, AT; Miranda, AC; Martins, AP; Bento, ASContext: The Study Team integrates researchers of: National Association of Pharmacies (ANF); NHS Primary Care Unit USF S. Julião of Agrupamento dos Centros de Saúde (ACeS) Baixo Mondego; National Oncology Registry (IPO Lisboa); Faculty of Pharmacy University of Lisbon; and Skaggs School of Pharmacy University of Colorado. The trial involves primary care and local pharmacies vs. usual fragmented care. Population...
Non-AIDS-Related Comorbidities in People Living with HIV-1 Aged 50 Years and Ol...
Serrão, R; Piñero, C; Velez, J; Coutinho, D; Maltez, F; Lino, S; Sarmento E Castro, R; Tavares, AP; Pacheco, P; Lopes, MJ; Mansinho, K; Miranda, ACObjective: To characterize the profile of non-AIDS-related comorbidities (NARC) in the older HIV-1-infected population and to explore the factors associated with multiple NARC. Methods: This was a multicentre, cross-sectional study including HIV-1-infected patients aged ≥50 years, who were virologically suppressed and had been on a stable antiretroviral therapy (ART) regimen for at least 6 months. A multiple re...
Non-AIDS-related comorbidities in people living with HIV-1 aged 50 years and ol...
Serrão, R; Piñero, C; Velez, J; Coutinho, D; Maltez, F; Lino, S; Sarmento, E; Castro, R; Tavares, AP; Pacheco, P; Lopes, MJ; Mansinho, K; Miranda, ACOBJECTIVE: To characterize the profile of non-AIDS-related comorbidities (NARC) in the older HIV-1-infected population and to explore the factors associated with multiple NARC. METHODS: This was a multicentre, cross-sectional study including HIV-1-infected patients aged ≥50 years, who were virologically suppressed and had been on a stable antiretroviral therapy (ART) regimen for at least 6 months. A multiple re...
HIV-2 Integrase Polymorphisms and Longitudinal Genotypic Analysis of HIV-2 Infe...
Cavaco-Silva, J; Abecasis, A; Miranda, AC; Poças, J; Narciso, J; Águas, MJ; Maltez, F; Almeida, I; Germano, I; Diniz, A; Gonçalves, MF; Gomes, PTo characterize the HIV-2 integrase gene polymorphisms and the pathways to resistance of HIV-2 patients failing a raltegravir-containing regimen, we studied 63 integrase strand transfer inhibitors (INSTI)-naïve patients, and 10 heavily pretreated patients exhibiting virological failure while receiving a salvage raltegravir-containing regimen. All patients were infected by HIV-2 group A. 61.4% of the integrase r...