4 documents found, page 1 of 1
Percepção do estado de saúde mental da população de Paredes de Coura
Camacho, Andrea; Miranda, Adriana; Ferreira, Inês; Barbosa, Mariana; Graça, L.C.C; Sá, DianaIntrodução: Apesar da conceção de Saúde Mental não ser consensual entre a população, a mesma é entendida como sendo um estado de bem-estar, através do qual o indivíduo consegue executar as suas capacidades em situações de stress, trabalhando de forma produtiva e frutífera para a comunidade onde se encontra inserido (Comissão das Comunidades Europeias [CCE], 2005). Assim, e uma vez que o enfermeiro assume um pap...
When a common complaint reveals an uncommon diagnosis – The Eagle syndrome
Fernandes, Dina Novais; Silva, António; Miranda, Adriana; Sousa, Luis; Sequeira, JoséIntroduction: The Eagle syndrome is characterized by the elongation of styloid process. This provides attachment for many important neurovascular structures and can lead to a broad spectrum of symptoms. The most common symptoms include odynophagia and a sensation of a foreign body. It can also cause dysphagia, headache, syncope, or even transient ischemic attacks. The diagnosis is difficult as the symptoms may ...
Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in an...
Castro, Andreia Cristiana Teixeira; Sousa, Ana Luísa Jales Monteiro; Esteves, Sofia; Santos, Liliana da Silva; Fernandes, Anabela SilvaPolyglutamine diseases are a class of dominantly inherited neurodegenerative disorders for which there is no effective treatment. Here we provide evidence that activation of serotonergic signalling is beneficial in animal models of Machado-Joseph disease. We identified citalopram, a selective serotonin reuptake inhibitor, in a small molecule screen of FDA-approved drugs that rescued neuronal dysfunction and red...
Eradication of Helicobacter pylori: the end of the line for standard triple the...
Silva, António Assunção; Macedo, Rui; Fernandes, Dina Novais; Sousa, Luís; Miranda, AdrianaObjectives: To review the evidence for the effectiveness of triple therapy (TT) and sequential therapy (TS) in the eradication of Helicobacter pylori infection (H. pylori). Data sources: MEDLINE and evidence-based medicine websites. Methods: We conducted a search for clinical practice guidelines (CPG), systematic reviews (SR), meta-analyses (MA) and randomized clinical trials (RCT), published between June, 2004...