3 documents found, page 1 of 1
Pioneering wound care solutions: triaxial wet-spun fibers with bioactive agents...
Miranda, Catarina Alexandra Fortuna Santos; Marinho, Elina Margarida Ribeiro; Rocha, Diana; Silva, C.; Silva, Maria Manuela; Schlapp-Hackl, IngeFiber-based constructs have been produced as an alternative to conventional dressings for the treatment of chronic wounds (CWs), showing good tenability, high surface area and regulable porosity. A commonly used technique for processing such dressings is wet-spinning, which involves precipitating a polymer solution into a coagulation bath containing a non-solvent of that polymer. This process produces fibers wi...
Pioneering wound care solutions: triaxial wet-spun fibers with bioactive agents...
Miranda, Catarina Alexandra Fortuna Santos; Silva, Ana Francisca Gomes da; Evenou, Camille; Lamartine, Jérôme; Fromy, BerengereThe incidence of bacterial infections associated with chronic wounds (CWs) has increased in recent years. Thus, a triaxial wet-spun fibrous system (containing three layers) was produced for CW healing. The triaxial fibers were loaded with cinnamon leaf oil (CLO), endowed with high antibacterial, antioxidant and anti-inflammatory features, and an antimicrobial peptide alaninealanineprolinevaline (AAPV) capable o...
Polycaprolactone/sodium alginate coaxial wetspun fibers modified with carbon na...
Marinho, Elina Margarida Ribeiro; Silva, Beatriz M.; Miranda, Catarina Alexandra Fortuna Santos; Pinho, Sonia L. C.; Felgueiras, Helena PradoChronic wounds (CWs) are a significant public health concern and affect 1–2% of the world’s population. They are responsible for high morbidity and mortality rates. Bacterial infections caused by Staphylococcus aureus and Pseudomonas aeruginosa are very common in CWs and prevent normal wound healing steps from taking place. Carbon nanofibers (CNFs) have attracted interest due to their inherent antibacterial and...