Encontrados 11 documentos, a visualizar página 1 de 2
Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by...
Rodrigues, Joana S.; Faria-Pereira, Andreia; Camões, Sérgio P.; Serras, Ana S.; Morais, Vanessa A.; Ruas, Jorge Lira; Miranda, Joana PIntroduction: The development of reliable hepatic in vitro models may provide insights into disease mechanisms, linking hepatocyte dysmetabolism and related pathologies. However, several of the existing models depend on using high concentrations of hepatocyte differentiation-promoting compounds, namely glucose, insulin, and dexamethasone, which is among the reasons that have hampered their use for modeling meta...
A observação interdisciplinar como contributo para o desenvolvimento pessoal e ...
Duarte, Cristina; Sanches, Tatiana; Miranda, Joana P; Batista, MarianaA presente comunicação resulta de reflexão conjunta no âmbito da Pós-Graduação em Pedagogia do Ensino Superior, do Instituto de Educação da Universidade de Lisboa, decorrente de trabalho de observação realizado por quatro docentes do ensino superior das áreas de Serviço Social, Educação, Ciências Farmacêuticas e Veterinária. Sendo a observação entre pares um espaço privilegiado para o desenvolvimento pessoal e ...
Pharmaceutical Sciences and Graduate Education: current and future challenges
Miranda, Joana P; Batista, Mariana; Duarte, Cristina; Sanches, TatianaIntroduction: The higher education of future pharmacists offers a wide, comprehensive range of education and education to accommodate a lifelong learning perspective and eventual learning along with professional mobility. However, it is necessary to ensure that students acquire, upon leaving university, competencies for the exercise of their future profession (1,2). Despite pharma's recent change in approach to...
3D-MSCs A151 ODN-Loaded Exosomes Are Immunomodulatory And Reveal A Proteomic Ca...
P Camões, Sérgio; Bulut, Ozlem; Yazar, Volkan; Gaspar, Maria Manuela; Simões, Sandra; Ferreira, Rita; Vitorino, Rui; Santos, Jorge M.; Gursel, IhsanIntroduction Non-healing wounds remain a major burden due to the lack of effective treatments. Mesenchymal stem cell-derived exosomes (MSC-Exo) have emerged as therapeutic options given their pro-regenerative and immunomodulatory features. Still, little is known on the exact mechanisms mediated by MSC-Exo. Importantly, modulation of their efficacy through 3D-physiologic cultures together with loading strategies...
Orientação pedagógica: estudo sobre as perceções, expectativas e necessidades d...
Duarte, Cristina; Sanches, Tatiana; Miranda, Joana P; Batista, Mariana; Gonçalves, Susana FilipaA presente comunicação integra a apresentação de resultados de um estudo que tem como objectivo compreender as percepções, expectativas e necessidades de alunos de doutoramento e doutorados face à orientação recebida ao longo do percurso académico. A recolha de dados foi realizada através de questionário e incluía as seguintes secções: dados sociodemográficos; aliança de aprendizagem entre o orientador e o orie...
Lessons, discoveries, challenges, and results in an interdisciplinary learning ...
Sanches, Tatiana; Duarte, Cristina; Batista, Mariana; Miranda, Joana PThe present study describes how a group of higher education teachers, from different disciplinary areas, came to constitute themselves as a learning community. Learning communities allow the exchange of information, tools, experiences, innovative practices, as well as knowledge transfer between colleagues in a faster and more relevant way. Despite the disciplinary diversity, the focus on university pedagogy gro...
Ph.D. supervision: doctoral students perceptions, expectations and needs
Gonçalves, Susana Filipa; Sanches, Tatiana; Batista, Mariana; Duarte, Cristina; Miranda, Joana PThis paper aims to understand the perceptions, expectations, and needs of Ph.D. students regarding the guidance received along the third cycle of higher education (doctoral degree). This goal is framed by the growth of challenges faced by higher education institutions, such as, the increasing number of doctoral programs and its demand. This has led to global competition, based also on the number of doctoral gra...
Interdisciplinary Class Observation in Higher Education: Lessons Learned from t...
Miranda, Joana P; Batista, Mariana; Duarte, Cristina Paula Pereira; Sanches, TatianaPeer observation of teaching has been adopted as a method to improve the quality of teaching. It involves observers providing descriptive feedback to their peers on learning and teaching practices. However, although extensively described in the literature in the education field, its use as a tool for development beyond teaching skills has not been explored deeply, nor the best practices described. Therefore, th...
Interdisciplinary Class Observation in Higher Education: Lessons Learned From t...
Miranda, Joana P; Batista, Mariana; Duarte, Cristina; Sanches, TatianaPeer observation of teaching has been adopted as a method to improve the quality of teaching. It involves observers providing descriptive feedback to their peers on learning and teaching practices. However, although extensively described in the literature in the education field, its use as a tool for development beyond teaching skills has not been explored deeply, nor the best practices described. Therefore, th...
A Critical Perspective on 3D Liver Models for Drug Metabolism and Toxicology St...
Serras, Ana S.; Rodrigues, Joana S.; Cipriano, Madalena; Rodrigues, Armanda V.; Oliveira, Nuno G; Miranda, Joana PThe poor predictability of human liver toxicity is still causing high attrition rates of drug candidates in the pharmaceutical industry at the non-clinical, clinical, and post-marketing authorization stages. This is in part caused by animal models that fail to predict various human adverse drug reactions (ADRs), resulting in undetected hepatotoxicity at the non-clinical phase of drug development. In an effort t...