2 documents found, page 1 of 1
Silk fibroin magnetoactive nanocomposite films and membranes for dynamic bone t...
Reizabal, A.; Brito-Pereira, R.; Fernandes, Margarida; Castro, N.; Correia, V.; Ribeiro, C.; Costa, C. M.; Perez, L.; Vilas, J. L.; Lanceros-Méndez, S.Bone-related diseases are one of the most common health conditions that limit the quality of life of elderly. Novel materials for bone tissue engineering that actively assist on the regeneration of bone tissue are thus needed. In this work, magnetoactive scaffolds comprised of silk fibroin (SF) with different content of filler cobalt ferrite nanoparticles were produced by solvent-casting and electrospinning tec...
Inherited p40phox deficiency differs from classic chronic granulomatous disease
van de Geer, A.; Nieto-Patlán, A.; Kuhns, D.; Tool, A.; Arias, A.; Bouaziz, M.; de Boer, M.; Franco, J.; Gazendam, R.; van Hamme, J.; van Houdt, M.Biallelic loss-of-function (LOF) mutations of the NCF4 gene, encoding the p40phox subunit of the phagocyte NADPH oxidase, have been described in only 1 patient. We report on 24 p40phox-deficient patients from 12 additional families in 8 countries. These patients display 8 different in-frame or out-of-frame mutations of NCF4 that are homozygous in 11 of the families and compound heterozygous in another. When ove...