5 documents found, page 1 of 1
Evidence for host epigenetic signatures arising from arbovirus infections: a sy...
Aguiar, Gabriella Pequeno Costa Gomes de; Leite, Claudio Manuel Gonçalves da Silva; Dias, Beatriz; Vasconcelos, Silvania Maria MendesBackground: Arbovirus infections have steadily become a major pandemic threat. This study aimed at investigating the existence of host epigenetic markers arising from the principal arboviruses infections impacting on human health. We set to systematically review all published evidence describing any epigenetic modifications associated with infections from arboviruses, including, but not limited to, microRNAs, D...
Hexane extracts of Calophyllum brasiliense inhibit the development of gastric p...
Lemos, Larissa M. S.; Miyajima, Fabio; Castilho, Geovane R. C.; Martins, Domingos Tabajara O.; Pritchard, D. Mark; Burkitt, Michael D.Objectives: Indigenous Latin American populations have used extracts from Calophyllum brasiliense, a native hardwood, to treat gastrointestinal symptoms for generations. The hexane extract of Calophyllum brasiliense stem bark (HECb) protects against ethanol-mediated gastric ulceration in Swiss–Webster mice. We investigated whether HECb inhibits the development of gastric epithelial pathology following Helicobac...
Development of ELISAs for diagnosis of acute typhoid fever in Nigerian children
Felgner, Jiin; Jain, Aarti; Nakajima, Rie; Liang, Li; Jasinskas, Algis; Gotuzzo, Eduardo; Vinetz, Joseph M.; Miyajima, Fabio; Pirmohamed, MunirImproved serodiagnostic tests for typhoid fever (TF) are needed for surveillance, to facilitate patient management, curb antibiotic resistance, and inform public health programs. To address this need, IgA, IgM and IgG ELISAs using Salmonella enterica serovar Typhi (S. Typhi) lipopolysaccharide (LPS) and hemolysin E (t1477) protein were conducted on 86 Nigerian pediatric TF and 29 non-typhoidal Salmonella (NTS) ...
Is the recent increment in attributable deaths to type- 2 diabetes (T2D) associ...
Cavalcanti, Luciano Pamplona de Góes; D’angelo, Sara Mendes; Lemos, Daniele Rocha Queiroz; Barreto, Francisca Kalline de AlmeidaIntroduction: Chikungunya virus (CHIKV) can negatively influence outcomes in patients with pre-existing conditions. We investigated the association between the recent CHIKV outbreak and increased type 2 diabetes (T2D)-attributable deaths. Methods: Monthly averages of T2D-attributable deaths between 2001 and 2016 were determined and compared to the equivalent data for 2017 and the recent CHIKV outbreak. Results:...
Aspectos fundamentais da validade juridica das provas em DNA
Miyajima, FabioOrientador : Miguel Morano Junior; Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba; Resumo: As investigações científicas que fundamentam as decisões jurídicas ganharam uma base extremamente sólida com os avanços alcançados na tecnologia em DNA. Os testes realizados com os ácidos nucléicos apresentam uma base de identificação positiva, permitindo aos peritos das...