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Poly-N-acetylglucosamine production by Staphylococcus epidermidis cells increas...

Ferreirinha, Pedro; Pérez-Cabezas, B.; Correia, A.; Miyazawa, B.; França, Ângela Maria Oliveira Sousa; Carvalhais, Virgínia Maria Dinis; Faustino, A.

Poly-N-acetyl glucosamine (PNAG) is a major component of Staphylococcus epidermidis biofilms extracellular matrix. However, it is not yet clear how this polysaccharide impacts the host immune response and infection-associated pathology. Faster neutrophil recruitment and bacterial clearance was observed in mice challenged intraperitoneally with S. epidermidis biofilm cells of the PNAG-producing 9142 strain than ...

Date: 2016   |   Origin: RepositóriUM - Universidade do Minho
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