11 documents found, page 1 of 2
Viral genetic clustering and transmission dynamics of the 2022 mpox outbreak in...
Borges, Vítor; Duque, Mariana Perez; Martins, João Vieira; Vasconcelos, Paula; Ferreira, Rita; Sobral, Daniel; Pelerito, Ana; de Carvalho, Isabel LopesPathogen genome sequencing during epidemics enhances our ability to identify and understand suspected clusters and investigate their relationships. Here, we combine genomic and epidemiological data of the 2022 mpox outbreak to better understand early viral spread, diversification and transmission dynamics. By sequencing 52% of the confirmed cases in Portugal, we identified the mpox virus sublineages with the hi...
Comparative Effectiveness of COVID-19 Vaccines in Preventing Infections and Dis...
Kislaya, Irina; Casaca, Pedro; Borges, Vítor; Sousa, Carlos; Ferreira, Bibiana I.; Fonte, Ana; Fernandes, Eugénia; Dias, Carlos Matias; Duarte, SílviaWe estimated comparative primary and booster vaccine effectiveness (VE) of SARS-CoV-2 Omicron BA.5 and BA.2 lineages against infection and disease progression. During April-June 2022, we implemented a case-case and cohort study and classified lineages using whole-genome sequencing or spike gene target failure. For the case-case study, we estimated the adjusted odds ratios (aORs) of vaccination using a logistic ...
LOCUS (LOng Covid-Understanding Symptoms, events and use of services in Portuga...
Dinis Teixeira, J.P.; Santos, Mário J.D.S.; Soares, Patricia; Azevedo, Luísa de; Barbosa, Patrícia; Boas, Andreia Vilas; Cordeiro, João V.; Dias, SóniaApproximately 10% of patients experience symptoms of Post COVID-19 Condition (PCC) after a SARS-CoV-2 infection. Akin acute COVID-19, PCC may impact a multitude of organs and systems, such as the cardiovascular, respiratory, musculoskeletal, and neurological systems. The frequency and associated risk factors of PCC are still unclear among both community and hospital settings in individuals with a history of COV...
Viral genetic clustering and transmission dynamics of the 2022 mpox outbreak in...
Borges, Vítor; Duque, Mariana Perez; Martins, João Vieira; Vasconcelos, Paula; Ferreira, Rita; Sobral, Daniel; Pelerito, Ana; de Carvalho, Isabel LopesPathogen genome sequencing during epidemics enhances our ability to identify and understand suspected clusters and investigate their relationships. Here, we combine genomic and epidemiological data of the 2022 mpox outbreak to better understand early viral spread, diversification and transmission dynamics. By sequencing 52% of the confirmed cases in Portugal, we identified the mpox virus sublineages with the hi...
Delta variant and mRNA COVID-19 vaccines effectiveness: higher odds of vaccine ...
Kislaya, Irina; Freire Rodrigues, Eduardo; Borges, Vítor; Gomes, João Paulo; Sousa, Carlos; Almeida, José Pedro; Peralta-Santos, André; Nunes, BaltazarInformation on COVID-19 vaccines' effectiveness and viral loads in vaccine infection breakthrough cases are critical to inform decision-makers. Few studies have compared the effectiveness of mRNA vaccines against Delta versus Alpha variant of concern (VOC) and estimated variant-specific viral loads in vaccine infection breakthroughs cases. We developed a case-case study to compare mRNA vaccines' effectiveness a...
Tracking SARS-CoV-2 lineage B.1.1.7 dissemination: insights from nationwide spi...
Borges, Vítor; Sousa, Carlos; Menezes, Luís; Gonçalves, António Maia; Picão, Miguel; Almeida, José Pedro; Vieita, Margarida; Santos, RafaelWe show that the SARS-CoV-2 B.1.1.7 lineage is highly disseminated in Portugal, with the odds of B.1.1.7 proportion increasing at an estimated 89% (95% confidence interval: 83-95%) per week until week 3 2021. RT-PCR spike gene target late detection (SGTL) can constitute a useful surrogate to track B.1.1.7 spread, besides the spike gene target failure (SGTF) proxy. SGTL/SGTF samples were associated with statisti...
A tale of two pandemics in three countries: Portugal, Spain, and Italy
Peralta-Santos, André; Saboga-Nunes, Luís; Magalhães, Pedro C.This chapter explores the structural similarities and differences between these three countries: on the one hand, in their respective health sectors’ capacities and reorganization; and on the other hand, in the different degrees of state capacity to respond to the pressing needs of their populations. In the last great epidemic, the 1918 flu, there was a transparent north-south gradient in the extent to which Eu...
Road Safety is No Accident: Challenges Facing the Healthcare Sector
Gomes, Bernardo; Peralta-Santos, André; Moitinho de Almeida, MariaN/a.; N/a.
Telehealth opportunities in the COVID-19 pandemic early days : what happened, d...
Amorim, Paula; Brito, Dulce; Castelo-Branco, Miguel; Fàbrega, Carles; Gomes da Costa, Fernando; Martins, Henrique; Gonçalves, LuisThe objective of this communication is to offer a better understanding of the value of telemedicine in health care, particularly its role in creating opportunities for continuity of care to patients in a complex and novel setting as were the circumstances of the early COVID-19 pandemic times. Crisis time is also a time for opportunities. With regard to telehealth, all players (providers, staff, and patients) sh...
Hospital Based Public Health Doctors: Just a Part of the Future
Peralta-Santos, André; Gomes, BernardoKeywords: Education, Public Health Professional; Portugal; Public Health/education.; Palavras-chave: Educação Profissional em Saúde Pública; Portugal; Saúde Pública/educação.