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Placental microphysiological systems: new advances on promising platforms that ...

Gonçalves, Inês M.; Afzal, Muhammad; Kennedy, Nithil; Moita, Ana; Lima, Rui Alberto Madeira Macedo; Ostrovidov, Serge; Hori, Takeshi; Nashimoto, Yuji

One of the most complex human physiological processes to study is pregnancy. Standard animal models, as well as two-dimensional models, lack the complexity and biological relevance required to accurately study such a physiological process. Recent studies have focused on the development of three-dimensional models based on microfluidic systems, designated as placental microphysiological systems (PMPSs). PMPS dev...


Thermal performance evaluation of pure PDMS and PDMS composites heat exchangers

Souza, Reinaldo; Nobrega, Glauco; Afonso, Inês Santos; Pereira, José; Cardoso, Elaine; Marques, Filipe; Vilarinho, Cândida; Moita, Ana; Lima, Rui A.

This study investigates the heat transfer performance of three types of heat exchangers: one made of pure polydimethylsiloxane (PDMS), another incorporating recycled graphite (PDMS + Graphite 30 mass%), and a third using commercial aluminium nanoparticles (PDMS + Aluminium 30 mass%). Thermal performance was evaluated by measuring the thermal conductivity of the materials, analysing experimental convection tests...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Projeto de Coliving

Moita, Ana

Sabe-se que o envelhecimento populacional é um dos principais desafios do século XXI. Paralelamente às transformações na estrutura familiar e à perda de algumas funções tradicionalmente cumpridas pela família, os idosos tornaram-se um dos grupos mais vulneráveis da nossa sociedade. Devido a estas alterações vividas no seio das famílias, é cada vez mais importante disponibilizar respostas que vão ao encontro das...


An overview of the recent advances in pool boiling enhancement materials, struc...

Pereira, José; Souza, Reinaldo; Lima, Rui Alberto Madeira Macedo; Moreira, António; Moita, Ana

This review attempts to provide a comprehensive assessment of recent methodologies, structures, and devices for pool boiling heat transfer enhancement. Several enhancement approaches relating to the underlying fluid route and the capability to eliminate incipient boiling hysteresis, augment the nucleate boiling heat transfer coefficient, and improve the critical heat flux are assessed. Hence, this study address...


Exploring heat exchange in space: recent advances in two-phase fluid experiment...

Nobrega, Glauco; Afonso, Inês Santos; Cardoso, Beatriz; Souza, Reinaldo Rodrigues de; Moita, Ana; Ribeiro, João Eduardo

Thermal regulation has assumed a central role in space expeditions ever since the inception of Sputnik-1 in 1957. Throughout the years, numerous techniques have been developed to regulate temperatures in spacecraft and space habitats. Initially, passive systems like heat shields and thermal linings were employed, while newer missions embrace active cooling using fluids like ammonia and water. With significant a...


Experimental evaluation of green nanofluids in heat exchanger made oF PDMS

Nobrega, Glauco; Souza, Reinaldo Rodrigues; Cardoso, Beatriz; Afonso, Inês; Pereira, José; Cardoso, Elaine; Moita, Ana; Ribeiro, João; Lima, Rui

Conventional methods for synthesizing metallic nanoparticles face challenges such as instability and environ mental concerns. Therefore, new, simpler, and more eco-friendly methods are being explored. In this context, the study reports a green synthesis process to produce magnetic iron oxide nanoparticles using an aqueous extract of the alga Chlorella vulgaris. This process leverages natural resources to create...


A review of novel heat transfer materials and fluids for aerospace applications

Nobrega, Glauco; Cardoso, Beatriz; Souza, Reinaldo; Pereira, José; Pontes, Pedro; Catarino, Susana Oliveira; Pinho, Diana

The issue of thermal control for space missions has been critical since the early space missions in the late 1950s. The demands in such environments are heightened, characterized by significant temperature variations and the need to manage substantial densities of heat. The current work offers a comprehensive survey of the innovative materials and thermal fluids employed in the aerospace technological area. In ...


Gestão da glicemia na parturiente com bomba de insulina

Moita, Ana

Para a mulher com diabetes mellitus tipo1, a maternidade apresenta desafios acrescidos que requerem intervenção especializada. Nestas situações, o papel do enfermeiro especialista em Enfermagem de Saúde Materna e Obstétrica, com a sua abordagem holística, revela-se fundamental para garantir uma gravidez, parto e puerpério isentos de riscos e complicações. A melhor e mais atual evidência científica demonstrou qu...


Organ-on-a-chip platforms for drug screening and delivery in tumor cells: a sys...

Gonçalves, Inês Maia Silva Rodrigo; Carvalho, Violeta Meneses; Rodrigues, Raquel Oliveira; Pinho, Diana; Teixeira, S. F. C. F.; Moita, Ana

The development of cancer models that rectify the simplicity of monolayer or static cell cultures physiologic microenvironment and, at the same time, replicate the human system more accurately than animal models has been a challenge in biomedical research. Organ-on-a-chip (OoC) devices are a solution that has been explored over the last decade. The combination of microfluidics and cell culture allows the design...


Experimental characterization of a microfluidic device based on passive crossfl...

Gonçalves, Inês M.; Castro, Inês; Barbosa, Filipe; Faustino, Vera; Catarino, Susana Oliveira; Moita, Ana; Miranda, João M.; Minas, Graça

The separation of red blood cells (RBCs) from blood plasma and the analysis of individual RBCs are of great importance, as they provide valuable information regarding the health of their donor. Recent developments in microfluidics and microfabrication have contributed to the fabrication of microsystems with complex features to promote the separation and analysis of RBCs. In this work, the separation capacity of...


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