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Protein profiling as early detection biomarkers for TiO2 nanoparticle toxicity ...

Sá-Pereira, Paula; Diniz, Mário S.; Moita, Liliana; Pinheiro, Teresa; Mendonça, E.; Paixão, Susana M.; Picado, Ana

ABSTRACT: The mode of action for nanoparticle (NP) toxicity in aquatic organisms is not yet fully understood. In this work, a strategy other than toxicity testing was applied to Daphnia magna exposed to TiO2-NPs: the use of nuclear microscopy and the assessment of protein profile. D. magna is a keystone species broadly used as a model system in ecotoxicology. Titanium (Ti) was found in the D. magna digestive tr...

Date: 2018   |   Origin: Repositório do LNEG

A multi-integrated approach on toxicity effects of engineered TiO2 nanoparticles

Picado, Ana; Paixão, Susana M.; Moita, Liliana; Silva, Luís; Diniz, M. S.; Lourenço, Joana; Peres, Isabel; Castro, Luísa; Correia, J.B.; Pereira, Joana

The new properties of engineered nanoparticles drive the need for new knowledge on the safety, fate, behavior and biologic effects of these particles on organisms and ecosystems. Titanium dioxide nanoparticles have been used extensively for a wide range of applications, e.g, self-cleaning surface coatings, solar cells, water treatment agents, topical sunscreens. Within this scenario increased environmental expo...

Date: 2015   |   Origin: Repositório do LNEG

A multi-integrated approach on toxicity effects of engineered TiO2 nanoparticles

Picado, Ana; Paixão, Susana M.; Moita, Liliana; Silva, Luis; Diniz, Mário S.; Lourenço, Joana; Peres, Isabel; Castro, Luisa; Correia, José Brito

The new properties of engineered nanoparticles drive the need for new knowledge on the safety, fate, behavior and biologic effects of these particles on organisms and ecosystems. Titanium dioxide nanoparticles have been used extensively for a wide range of applications, e.g, self-cleaning surface coatings, solar cells, water treatment agents, topical sunscreens. Within this scenario increased environmental expo...


Nuclear microscopy as a tool in TiO2 nanoparticles bioaccumulation studies in a...

Pinheiro, Teresa; Moita, Liliana; Silva, Luís; Mendonça, E.; Picado, Ana

Engineered Titanium nanoparticles are used for a wide range of applications from coatings, sunscreen cosmetic additives to solar cells or water treatment agents. Inevitably environmental exposure can be expected and data on the ecotoxicological evaluation of nanoparticles are still scarce.The potential effects of nanoparticles of titanium dioxide (TiO2) on two model organisms, the water flea, Daphnia magna and ...

Date: 2013   |   Origin: Repositório do LNEG

Effects of engineered nanoTi02 on aquatic species

Picado, Ana; Moita, Liliana; Paixão, Susana M.; Silva, Luís; Diniz, M. S.; Mendonça, E.

Date: 2012   |   Origin: Repositório do LNEG

Nuclear Microscopy as a tool in nano TiO2 Bioaccumulation Studies in aquatic sp...

Pinheiro, Teresa; Moita, Liliana; Silva, Luís; Mendonça, E.; Picado, Ana

Date: 2012   |   Origin: Repositório do LNEG

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