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A Novel Quantitative Fluorescent Reporter Assay for RAG Targets and RAG Activity

Trancoso, Inês; Bonnet, Marie; Gardner, Rui; Carneiro, Jorge; Barreto, Vasco M.; Demengeot, Jocelyne; Sarmento, Leonor M.

Recombination-Activating Genes (RAG) 1 and 2 form the site specific recombinase that mediates V(D)J recombination, a process of DNA editing required for lymphocyte development and responsible for their diverse repertoire of antigen receptors. Mistargeted RAG activity associates with genome alteration and is responsible for various lymphoid tumors. Moreover several non-lymphoid tumors express RAG ectopically. A ...


Validation and quality assurance applied to goat milk chemical composition: min...

Trancoso, Inês; Roseiro, Luisa B.; Martins, António P. L.; Trancoso, Maria Ascensão

In the present study, quality assurance programmes were implemented to validate and control the analytical methodologies used for the characterization of minerals and trace elements in goat milk from Portuguese breeds. With the exception of chloride that was determined by potentiometric titration, all the other elements were determined by spectroscopic techniques after different sample decomposition: P was meas...

Date: 2009   |   Origin: Repositório do LNEG

Minerals and trace elements from milk of indigenous Portuguese goat breads: pre...

Trancoso, Inês; Trancoso, Maria Ascensão; Martins, António P. L.; Roseiro, Luisa B.

Date: 2008   |   Origin: Repositório do LNEG

Validation and quality assurance applied to goat milk chemical composition

Trancoso, Inês; Roseiro, Luisa B.; Martins, António P. L.; Trancoso, Maria Ascensão

Date: 2008   |   Origin: Repositório do LNEG

Minerals and trace elements from milk of indigenous Portuguese goat breads: pre...

Trancoso, Inês; Trancoso, Maria Ascensão; Martins, António P. L.; Roseiro, Luisa B.

Date: 2008   |   Origin: Repositório do LNEG

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