13 documents found, page 1 of 2

Caracterização molecular do gene env de estirpes primárias VIH-2 CCR5/CXCR4 ind...

Functional analysis of vif protein shows less restriction of human immunodefici...

Viral infectivity factor (Vif) is one of the human immunodeficiency virus (HIV) accessory proteins and is conserved in the primate lentivirus group. This protein is essential for viral replication in vivo and for productive infection of nonpermissive cell

HIV-2 infection and chemokine receptors usage - Clues to reduced virulence of H...

Human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) are the causative agents of Acquired Immunodeficiency Syndrome (AIDS). Without therapeutic intervention, HIV-1 or HIV-2 infections in humans are characterized by a gradual and irreversible imm

Functional characterization of the gp105 of primary HIV-2 strains unable to use...

Camelized rabbit-derived VH single-domain Intrabodies Against vif strongly neut...

We recently developed a specific single-chain antibody from immunized rabbits to HIV-1 Vif protein that was expressed intracellularly and inhibited reverse transcription and viral replication. The Vif of HIV-1 overcomes the innate antiviral activity of a

pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates in...

The nucleotide sequences of the pncA genes within 55 multidrug-resistant pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates were determined. Fifty-three out of the 55 isolates were pyrazinamidase (PZase) negative. Four strains contained a

Construction and characterization of CD4-independent infectious recombinant HIV...

Human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) differ in their pathogenic mechanisms as evidenced by lower rate of disease progression. lower transmission rates and lower viral load in peripheral blood for HIV-2. One of the many factors th

Selected lipids activate phagosome actin assembly and maturation resulting in k...

Pathogenic mycobacteria such as Mycobacterium tuberculosis and Mycobacterium avium facilitate disease by surviving intracellularly within a potentially hostile environment: the macrophage phagosome. They inhibit phagosome maturation processes, including f

Identification and characterization of HIV-2 strains obtained from asymptomatic...

In vivo, human immunodeficiency virus type 2 (HIV-2) infection reveals several unique characteristics when compared to HIV-1 infection, the most remarkable of which is the extraordinarily long asymptomatic period. Here we describe two HIV-2 primary isolat

Phenotypic identification of HIV-2 protease resistance mutations by recombinant...