8 documents found, page 1 of 1
Emergence of ST131 carrying carbapenemase genes, European Union/European Econom...
Kohlenberg, Anke; Svartström, Olov; Apfalter, Petra; Hartl, Rainer; Bogaerts, Pierre; Huang, Te-Din; Chudejova, Katerina; Malisova, LuciaAnalysis of 594 isolates of sequence type (ST)131 and its single locus variants carrying carbapenemase genes from 17 European Union/European Economic Area countries revealed acquisition of 18 carbapenemase variants, mainly in ST131 clades A and C. Most frequent were (n = 230) and (n = 224), detected in 14 and 12 countries, respectively. Isolates carrying have increased rapidly since 2021. The increasing detecti...
Rapid cross-border emergence of NDM-5-producing Escherichia coli in the Europea...
Linkevicius, Marius; Bonnin, Rémy A.; Alm, Erik; Svartström, Olov; Apfalter, Petra; Hartl, Rainer; Hasman, Henrik; Roer, Louise; Räisänen, KatiWhole genome sequencing data of 874 Escherichia coli isolates carrying bla NDM-5 from 13 European Union/European Economic Area countries between 2012 and June 2022 showed the predominance of sequence types ST167, ST405, ST410, ST361 and ST648, and an increasing frequency of detection. Nearly a third (30.6%) of these isolates were associated with infections and more than half (58.2%) were predicted to be multidr...
Worsening epidemiological situation of carbapenemase-producing Enterobacteriace...
Brolund, Alma; Lagerqvist, Nina; Byfors, Sara; Struelens, Marc J.; Monnet, Dominique L.; Albiger, Barbara; Kohlenberg, AnkeA survey on the epidemiological situation, surveillance and containment activities for carbapenemase-producing Enterobacteriaceae (CPE) was conducted in European countries in 2018. All 37 participating countries reported CPE cases. Since 2015, the epidemiological stage of CPE expansion has increased in 11 countries. Reference laboratory capability, dedicated surveillance and a specific national containment plan...
Strong correlation between the rates of intrinsically antibiotic-resistant spec...
Jarlier, Vincent; Diaz Högberg, Liselotte; Heuer, Ole E.; Campos, José; Eckmanns, Tim; Giske, Christian G.; Grundmann, Hajo; Johnson, Alan PBackground: Antibiotic resistance, either intrinsic or acquired, is a major obstacle for treating bacterial infections.AimOur objective was to compare the country-specific species distribution of the four Gram-negative species Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter species and the proportions of selected acquired resistance traits within these species.MethodWe used dat...
Attributable deaths and disability-adjusted life-years caused by infections wit...
Cassini, Alessandro; Högberg, Liselotte Diaz; Plachouras, Diamantis; Quattrocchi, Annalisa; Hoxha, Ana; Simonsen, Gunnar Skov; Colomb-Cotinat, MélanieBackground: Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging. We aimed to estimate the burden of infections caused by antibiotic-resistant bacteria of public health concern in countries of the EU and European Economic Area (EEA) in 2015, measured in number of cases, attributable death...
Livestock-associated meticillin-resistantStaphylococcus aureus(MRSA) among huma...
Kinross, Pete; Petersen, Andreas; Skov, Robert; Van Hauwermeiren, Evelyn; Pantosti, Annalisa; Laurent, Frédéric; Voss, Andreas; Kluytmans, JanCurrently, surveillance of livestock-associated meticillin-resistantStaphylococcus aureus(LA-MRSA) in humans in Europe is not systematic but mainly event-based. In September 2014, the European Centre for Disease Prevention and Control (ECDC) initiated a questionnaire to collect data on the number of LA-MRSA from human samples (one isolate per patient) from national/regional reference laboratories in European Un...
Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia col...
Grundmann, Hajo; Glasner, Corinna; Albiger, Barbara; Aanensen, David M.; Tomlinson, Chris T.; Andrasević, Arjana Tambić; Cantón, Rafael; Carmeli, YehudaBACKGROUND: Gaps in the diagnostic capacity and heterogeneity of national surveillance and reporting standards in Europe make it difficult to contain carbapenemase-producing Enterobacteriaceae. We report the development of a consistent sampling framework and the results of the first structured survey on the occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in European hospitals. M...
Carbapenemase-producing Enterobacteriaceaein Europe: assessment by national exp...
Albiger, Barbara; Glasner, Corinna; Struelens, Marc J.; Grundmann, Hajo; Monnet, Dominique L.In 2012, the European Centre for Disease Prevention and Control (ECDC) launched the 'European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE)' project to gain insights into the occurrence and epidemiology of carbapenemase-producing Enterobacteriaceae (CPE), to increase the awareness of the spread of CPE, and to build and enhance the laboratory capacity for diagnosis and surveillance of CPE in Eur...