4 documents found, page 1 of 1
Dementia in 16th-Century Medical Practice: Amato Lusitano
de Mendonça, Alexandre; Montalvo, Alexandre; Oliveira, Victor.; .
Long-term predictive accuracy of the ‘mild cognitive impairment due to Alzheime...
Cardoso, Sandra; Montalvo, Alexandre; Maroco, João; Silva, Dina; Alves, Luísa; Guerreiro, Manuela; Mendonça, Alexandre deBackground: The development and clinical use of biomarkers has dramatically changed the framework of Alzheimer’s disease (AD) management, allowing the diagnosis at the mild cognitive impairment (MCI) stage. In 2015 we compared the prevalence and prognosis of AD at the MCI stage according to different criteria available at that time, and we found that the National Institute of Aging-Alzheimer Association (NIA-AA...
Amyloid-negative, neurodegeneration-negative amnestic mild cognitive impairment
Cardoso, Sandra; Guerreiro, Manuela; Montalvo, Alexandre; Silva, Dina; Alves, Luísa; Mendonça, Alexandre deBackground:The concept of amnestic mild cognitive impairment (aMCI) was developed to identify patients at an initial stage of Alzheimer's disease (AD). However, some patients with aMCI do not present biomarkers of amyloid pathology or neuronal injury.Objective:To know the natural history of amyloid-negative and neurodegeneration-negative patients with aMCI, namely to ascertain: 1) whether these patients remain ...
Benign fasciculations: a follow‐up study with electrophysiological studies
Montalvo, Alexandre; Swash, Michael; Carvalho, MamedeIntroduction/aims: Fasciculations can be symptomatic, yet not progress to amyotrophic lateral sclerosis (ALS), a condition categorized as benign fasciculation syndrome (BFS). We aimed to assess electrodiagnostic changes and clinical course over time in patients with BFS. Methods: This was a retrospective review of medical records of patients who were referred because of a suspicion of ALS or who had directly as...