Made available in DSpace on 2022-04-29T08:46:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2001-01-01; In the area of drug discovery, natural products represent a myriad of templates for new lead discovery. It is, however, most unlikely that the bioactive principle itself shall become a drug; it is much more likely that a medicinal chemistry project needs to be initiated as soon the potency or selectivit...