4 documents found, page 1 of 1
The challenge of implementing Less is More medicine : a european perspective
Kherad, Omar; Peiffer-Smadja, Nathan; Karlafti, Lina; Lember, Margus; Aerde, Nathalie Van; Gunnarsson, Orvar; Baicus, Cristian; Vieira, Miguel BigotteThe concept of Less is More medicine emerged in North America in 2010. It aims to serve as an invitation to recognize the potential risks of overuse of medical care that may result in harm rather than in better health, tackling the erroneous assumption that more care is always better. In response, several medical societies across the world launched quality-driven campaigns (“Choosing Wisely”) and published “top...
Chronic treatment with ivabradine does not affect cardiovascular autonomic cont...
Silva, Fernanda Cacilda dos Santos; Paiva, Franciny Aparecida; Ribeiro, Flavia Camargos de Figueiredo Müller; Caldeira, Henrique Martins ArantesA low resting heart rate (HR) would be of great benefit in cardiovascular diseases. Ivabradine-a novel selective inhibitor of hyperpolarization-activated cyclic nucleotide gated (HCN) channels- has emerged as a promising HR lowering drug. Its effects on the autonomic HR control are little known. This study assessed the effects of chronic treatment with ivabradine on the modulatory, reflex and tonic cardiovascul...
Contribution of autonomic reflexes to the hyperadrenergic state in heart failure
Montano, Nicola
Acute adenosine increases cardiac vagal and reduces sympathetic efferent nerve ...
Montano, Nicola