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Venom of the giant ant Dinoponera quadriceps attenuates inflammatory pain in mo...

Assreuy, Ana Maria Sampaio; Adjafre, Beatriz Lima; Sousa, Évilla Rayanne Oliveira; Alves, Ana Paula Negreiros Nunes; Pires, Alana de Freitas

Arthropod venoms are potential sources of bioactive substances, providing tools for the validation of popular use and new drugs design. Ants belonging to the genus Dinoponera are used in the folk medicine to treat inflammatory conditions. It was previously demonstrated that the venom of the giant ant Dinoponera quadriceps (DqV), containing a mixture of polypeptides, elicit antinociceptive effect in mi...

Date: 2022   |   Origin: Oasisbr

Núcleo de Estudo em Pacientes Especiais (NEPE): desafios e impactos

Carvalho Neto, Geraldo Lopes Bezerra de; Feitosa, Márcia Eugênia de Sousa Damasceno; Nascimento, Isabelly Vidal do; Dantas, Thinali Sousa

O Ceará possui uma parcela significativa da população com alguma necessidade especial, como doenças crônico-degenerativas, infectocontagiosas e estados sindrômicos, que muitas vezes necessitam de atenção especializada e prioridade no sistema de saúde. O Núcleo de Estudos em Pacientes Especiais (NEPE) foi criado em 1997 no Curso de Odontologia da Universidade Federal do Ceará, com o objetivo de promover conhecim...

Date: 2021   |   Origin: Oasisbr

Traumatismo dentário : da infância à idade adulta

Mota, Mário Rogério Lima; Chaves, Igor Carvalho; Ferreira, Gabriela de Sena; Oliveira, Victória Geisa Brito de; Aguiar, Airam Ferandes de

O projeto Dr. Sorriso é vinculado à Universidade Federal do Ceará, composto por 14 integrantes: 12 bolsistas do programa de educação tutorial – PET Odontologia UFC e um bolsista de extensão, sob orientação do Prof. Dr. Mário Rogério Lima Mota. O Grupo atua junto às instituições Associação Pestalozzi de Fortaleza e a Associação de Pais, Amigos e Pessoas com Deficiência de Funcionários do Banco do Brasil e da Com...

Date: 2021   |   Origin: Oasisbr

Manual de fluoretação: desmistificando o uso de de fluoretos

Mota, Mário Rogério Lima; Chaves, Igor Carvalho; Estellita, Maria Clara Ayres; Ferreira, Gabriela de Sena; Oliveira, Victória Geisa Brito de

O Programa de Educação Tutorial (PET) Odontologia da Universidade Federal do Ceará iniciou suas atividades em 1988 e desde então promove e incentiva a pesquisa, o ensino e a extensão universitária. O grupo conta com doze acadêmicos integrantes e um professor tutor. Entre os acadêmicos, o grupo é composto por integrantes do 3º ao 8º período. A tutoria do grupo PET, atualmente, está a cargo do Prof. Dr. Mário Rog...

Date: 2021   |   Origin: Oasisbr

Venom of the giant ant Dinoponera quadriceps attenuates inflammatory pain in mo...

Assreuy, Ana Maria Sampaio; Adjafre, Beatriz Lima; Sousa, Évilla Rayanne Oliveira; Alves, Ana Paula Negreiros Nunes; Pires, Alana de Freitas

Arthropod venoms are potential sources of bioactive substances, providing tools for the validation of popular use and new drugs design. Ants belonging to the genus Dinoponera are used in the folk medicine to treat inflammatory conditions. It was previously demonstrated that the venom of the giant ant Dinoponera quadriceps (DqV), containing a mixture of polypeptides, elicit antinociceptive effect in mice models ...

Date: 2020   |   Origin: Oasisbr

Effects of dexamethasone and nimesulide on bisphosphonate-related osteonecrosis...

Oliveira, Camila Carvalho de; Silva, Paulo Goberlânio de Barros; Ferreira Jr., Antonio Ernando Carlos; Gonçalves, Romélia Pinheiro

Objective: To evaluate the e ff ects of dexamethasone (DEX) and nimesulide (NIM) on Bisphosphonate-related Osteonecrosis of the Jaw (BRONJ) in rats. Design: BRONJ was induced by zoledronic acid (ZA) infusion (0.2 mg/kg) in Wistar rats (n = 8), followed by extraction of the left lower fi rst molar (BRONJ groups). Control groups (n = 40) received saline (IV). For eight weeks, DEX (0.04, 0.4, 4 mg/kg) or saline (S...

Date: 2018   |   Origin: Oasisbr

Association of the profile of individuals with cleft lip/palate with the beginn...

Moreira, Madiana Magalhães; Rebouças, Pedro Diniz; Chagas, Maria Lúcia Bonfim; Félix, Luan Cartaxo; Silva, Paulo Goberlânio de Barros

Introduction: Cleft lip and palate (CLP) is the most frequent congenital malformation among the anomalies of the head and neck. The orthopedic/orthodontic treatment is included in the rehabilitation of these individuals, however there is no consensus in the literature regarding the ideal time for its beginning. Objective: To verify and characterize the profile of individuals with CLP treated at a reference hosp...

Date: 2018   |   Origin: Oasisbr

Calycophyllum spruceanum BENTH ameliorates acute inflammation in mice

Silva, Ana Paula Azevedo Barros da; Amorim, Renata Morais Ferreira; Lopes, Roberta de Freitas; Mota, Mário Rogério Lima; Silva, Felipe Moura Araújo da

Ethnopharmacological relevance: Calycophyllum spruceanum (Benth.) Hook. F. ex K. Schum. is widely distributed in the Amazonian region of Brazil, where it is popularly known as “mulateiro”, “pau-mulato”, “pau-mulato-devárzea”, “escorrega-macaco” or “pau-marfim”. Preparations of C. spruceanum barks are used in the form of tea, poultice or skin patches to treat stomach diseases, skin inflammation and uterus tumors...

Date: 2018   |   Origin: Oasisbr

TNF-alpha expression, evaluation of collagen, and TUNEL of Matricaria recutita ...

Oliveira, Bruna Vasconcelos; Silva, Paulo Goberlânio de Barros; Nojosa, Jacqueline Santiago; Brizeno, Luiz André Cavalcante; Ferreira, Jamile Magalhães

OBJECTIVES: Characterize the cell profile and immunostaining of proinflammatory markers in an experimental model of bisphosphonate-related osteonecrosis of the jaw (BRONJ). MATERIALS AND METHODS: Male Wistar rats (n = 6– 7) were treated chronically with saline solution or zoledronic acid (ZA) at 0.04, 0.20, and 1.00 mg kg 1 (1.4 3 10 7, 6.9 3 10 6, and 3.4 3 10 5 mol kg 1), and subsequently, the first left inferio...

Date: 2017   |   Origin: Oasisbr

Immune cellular profile of bisphosphonate-related osteonecrosis of the jaw

Silva, Paulo Goberlândio de Barros; Oliveira, C. C. de; Brizeno, Luiz André Cavalcante; Wong, Deysi V. T.; Lima Júnior, Roberto César Pereira

OBJECTIVES: Characterize the cell profile and immunostaining of proinflammatory markers in an experimental model of bisphosphonate-related osteonecrosis of the jaw (BRONJ). MATERIALS AND METHODS: Male Wistar rats (n = 6-7) were treated chronically with saline solution or zoledronic acid (ZA) at 0.04, 0.20, and 1.00 mg kg(-1) (1.4 × 10(-7) , 6.9 × 10(-6) , and 3.4 × 10(-5) mol kg(-1) ), and subsequently, the fir...

Date: 2017   |   Origin: Oasisbr

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