A promoção da educação literária em contexto escolar requer abordagens criativas que respondam às necessidades e motivações dos alunos de hoje. Neste sentido, o recurso a estratégias de gamificação, como o Escape Room Digital, pode constituir uma via promissora para consolidar aprendizagens, desenvolver competências leitoras e despertar o gosto pela literatura. O presente projeto resulta de uma proposta desenvo...
Enquadramento: O Daratumumab (anti-CD38) é um anticorpo monoclonal IgG amplamente utilizado no tratamento de doenças hemato-oncológicas como no caso do Mieloma Múltiplo (MM). O Daratumumab liga-se ao CD38 expresso pelos eritrócitos causando uma panaglutinação nos testes pré-transfusionais, nomeadamente Pesquisa de Anticorpos Irregulares (PAI) e Provas de Compatibilidade (PC) [1]. O reagente Ditiotreitol (DTT) t...
The widespread accessibility of Generative Artificial Intelligence (GenAI) presents significant challenges to teachers, particularly within the context of Higher Education. According to a recent systematic literature review focused on higher education teachers and students, the latter group appears more receptive to these technologies, acknowledging both the opportunities and challenges they entail. In contrast...
Background and aim: Recreational use of anesthetic and sedative agents in health care practitioners is becoming an increasing problem due to its easy availability and, therefore, they become vulnerable to misusing or abusing of these drugs. The authors present a fatal case involving a a 50-year-old man, nurse, found dead in a hospital room, in supine position, with intravenous access devices in the forearm that...
Neste artigo é feita, numa primeira parte, uma análise crítica das vantagens e desvantagens do uso das tecnologias digitais no contexto educativo, complementada com uma breve reflexão sobre os desafios que se colocam aos agentes educativos na era digital. Afunilando o foco para o ensino da leitura e da escrita, na segunda parte é apresentado o recurso digital EAP - Ensinar e Aprender Português, que tem como obj...
Background and aim: Marijuana, hashish and other psychoactive products obtained from Cannabis are the most produced and trafficked illicit drugs around the world. Methods: The authors studied all the positive cases for cannabinoids in the Centre of Portugal; from autopsies at the Forensic Clinical and Pathology Service of Coimbra’s Delegation of the National Institute of Legal Medicine and Forensic Sciences (NI...
Due to the high prevalence of cannabinoids in forensic toxicology analysis, it is crucial to have an efficient method that allows the use of a small sample amount and that requires a minimal sample preparation for the determination and quantification of low concentrations. A simple, highly selective and high throughput liquid chromatography–tandem mass spectrometry methodology (LC–MS-MS-MS3) was developed for t...
Due to the high prevalence of cannabinoids in forensic toxicology, it is crucial to have an efficient method that allows the use of a small sample amount and that requires a minimal sample preparation, for the determination and quantification of low concentrations. A simple, highly selective and high throughput liquid chromatography tandem mass spectrometry method (LC-MS/MS-MS3) was developed for the determinat...
The present study aims to reflect on the oral health status of the elderly, addressing periodontal disease, as well as the importance of oral health, general health and quality of life. The methodology adopted consisted of a bibliographic research of scientific articles indexed in PUBMED® and Google Scholar® with the following combined keywords: “Periodontal Disease”, “Gerodontology”, “Oral Health”, “Elderly” a...