16 documents found, page 1 of 2
In vitro optimization of photobiomodulation and ultrasound stimulation protocol...
Monteiro, Francisca; Oliveira, Sofia; Marques, Carlos; Papadimitriou, Georgia; Silva, Joana M.; Padrão, Jorge; Sotiropoulos, Ioannis; Catarino, SusanaThe effectiveness of transcranial photobiomodulation (tPBM) and ultrasound stimulation (tUS) to mitigate different neuropathological mechanisms and stimulate neuroprotective responses has been vastly demonstrated in preclinical disease models. However, the translation into clinics is still suboptimal, revealing the need for more solid basic research to ascertain the most effective stimulation parameters to modu...
What Is the Impact of Antibiotic Resistance Determinants on the Bacterial Death...
Luz, Bruno T. S.; Rebelo, João S.; Monteiro, Francisca; Dionisio, FranciscoObjectives: Antibiotic-resistant bacteria are widespread, with resistance arising from chromosomal mutations and resistance genes located in the chromosome or in mobile genetic elements. While resistance determinants often reduce bacterial growth rates, their influence on bacterial death under bactericidal antibiotics remains poorly understood. When bacteria are exposed to bactericidal antibiotics to which they...
Devices used for photobiomodulation of the brain-a comprehensive and systematic...
Fernandes, Filipa; Oliveira, Sofia; Monteiro, Francisca; Gasik, Michael; Silva, Filipe Samuel; Sousa, Nuno; Carvalho, Óscar; Catarino, Susana OliveiraA systematic review was conducted to determine the trends in devices and parameters used for brain photobiomodulation (PBM). The revised studies included clinical and cadaveric approaches, in which light stimuli were applied to the head and/or neck. PubMed, Scopus, Web of Science and Google Scholar databases were used for the systematic search. A total of 2133 records were screened, from which 97 were included ...
Influence of ultrasound stimulation on the viability, proliferation and protein...
Pascoal, Selma; Oliveira, Sofia; Monteiro, Francisca; Padrão, Jorge; Costa, Rita; Zille, Andrea; Catarino, Susana Oliveira; Silva, Filipe S.Among the adjunctive procedures to accelerate orthodontic tooth movement (OTM), ultrasound (US) is a nonsurgical form of mechanical stimulus that has been explored as an alternative to the currently available treatments. This study aimed to clarify the role of US in OTM by exploring different stimulation parameters and their effects on the biological responses of cells involved in OTM. Human fetal osteoblasts a...
Assessing the influence of ultrasound stimulation parameters in neuronal-like c...
Monteiro, Francisca; Oliveira, Sofia; Catarino, Susana Oliveira; Sotiropoulos, Ioannis; Carvalho, Óscar Samuel Novais; Silva, Filipe S.Alzheimer’s disease (AD) is a neurodegenerative disorder that represents the most common cause of dementia, but recent efforts to develop effective pharmacological treatments have been disappointing. However, non-drug solutions have been proposed to block disease progression and alleviate clinical symptoms, demonstrating promising results. Transcranial ultrasound stimulation is at the forefront of alternative t...
The Impact of Non-Pathogenic Bacteria on the Spread of Virulence and Resistance...
Dionisio, Francisco; Domingues, Célia P. F.; Rebelo, João S.; Monteiro, Francisca; Nogueira, TeresaThis review discusses the fate of antimicrobial resistance and virulence genes frequently present among microbiomes. A central concept in epidemiology is the mean number of hosts colonized by one infected host in a population of susceptible hosts: R0. It characterizes the disease’s epidemic potential because the pathogen continues its propagation through susceptible hosts if it is above one. R0 is proportional ...
The Impact of Non-Pathogenic Bacteria on the Spread of Virulence and Resistance...
Dionisio, Francisco; Domingues, Célia P. F.; Rebelo, João S.; Monteiro, Francisca; Nogueira, TeresaThis review discusses the fate of antimicrobial resistance and virulence genes frequently present among microbiomes. A central concept in epidemiology is the mean number of hosts colonized by one infected host in a population of susceptible hosts: R0. It characterizes the disease’s epidemic potential because the pathogen continues its propagation through susceptible hosts if it is above one. R0 is proportional ...
An annotated checklist of the vascular flora of Quiçama National Park, Angola
Monteiro, Francisca; Costa, Esperança; Kissanga, Raquel; Costa, José Carlos; Catarino, LuísThe Quiçama National Park (PNQ), located in Luanda Province, Angola, is one of the oldest protected areas in the country. Although some work has been done on the flora of the Park, up to now a comprehensive record of the vascular plant species has been lacking. The objective of the present study was to produce an inventory of the vascular plant diversity of PNQ, as well as to record the types of vegetation in w...
Bacterial persistence is essential for susceptible cell survival in indirect re...
Rebelo, João; Domingues, Célia P. F.; Monteiro, Francisca; Nogueira, Teresa; Dionisio, FranciscoAntibiotic-susceptible bacteria may survive bactericidal antibiotics if other co-inhabiting bacteria detoxify the medium through antibiotic degradation or modification, a phenomenon denominated as indirect resistance. However, it is unclear how susceptible cells survive while the medium is still toxic. One explanation relies on the speed of detoxification, and another, non-exclusive explanation, relies on persi...
Harmful behaviour through plasmid transfer: a successful evolutionary strategy ...
Domingues, Célia P. F.; Rebelo, João S.; Monteiro, Francisca; Nogueira, Teresa; Dionisio, FranciscoConjugative plasmids are extrachromosomal mobile genetic elements pervasive among bacteria. Plasmids' acquisition often lowers cells' growth rate, so their ubiquity has been a matter of debate. Chromosomes occasionally mutate, rendering plasmids cost-free. However, these compensatory mutations typically take hundreds of generations to appear after plasmid arrival. By then, it could be too late to compete with f...