7 documents found, page 1 of 1
Optimization of therapeutic ultrasound stimulation to increase cells´ viability...
Oliveira, Sofia; Padrão, Jorge; Catarino, Susana Oliveira; Monteiro, Francisca Machado; Zille, Andrea; Silva, Filipe Samuel; Hinckel, Betina B.Objective: Therapeutic ultrasound (US) has been suggested to treat several human tissues due to its potential to promote cells´ activity. This study envisaged the establishment of an optimized US protocol to enhance cellular viability and proliferation. Methods: Human-derived cells were exposed daily or every other day to US for three days. Different central frequencies (0.45, 0.66, 1.00, 1.25, 1.50 and 2.00 MH...
Optimization of a photobiomodulation protocol to improve the cell viability, pr...
Gonçalves, Aline; Monteiro, Francisca Machado; Oliveira, Sofia; Costa, Inês; Catarino, Susana Oliveira; Carvalho, Óscar Samuel Novais; Padrão, JorgeNumerous pieces of evidence have supported the therapeutic potential of photobiomodulation (PBM) to modulate bone remodeling on mechanically stimulated teeth, proving PBM's ability to be used as a coadjuvant treatment to accelerate orthodontic tooth movement (OTM). However, there are still uncertainty and discourse around the optimal PBM protocols, which hampers its optimal and consolidated clinical applicabili...
Mechanical stimulation of human chondrocytes by ultrasound as a bioinspired str...
Oliveira, Sofia; Padrão, Jorge; Catarino, Susana Oliveira; Monteiro, Francisca Machado; Zille, Andrea; Silva, Filipe Samuel; Hinckel, Betina[Excerpt] Articular cartilage is naturally subjected to mechanical forces during knee joint loading. A constant and physiological loading of articular cartilage is essential for chondrocytes, the resident cells, that sense the mechanical deformations, activating their intracellular mechanisms to regulate and maintain the tissue homeostasis. However, either excessive or low magnitude mechanical loading may distu...
Interceptive treatment with Invisalign® First in moderate and severe cases: a c...
Pinho, Teresa; Rocha, Duarte; Ribeiro, Sofia; Monteiro, Francisca Machado; Pascoal, Selma; Azevedo, RuiThe increasing demand for more aesthetic/comfortable orthodontic alternatives fostered the utilization of clear aligners in recent years. However, the efficacy of clear aligners for treating complex malocclusions is often treated with scepticism. This case series aims to evaluate the predictability of the Invisalign<sup>®</sup> First system in moderate and severe cases requiring interceptive orthodontic treatme...
How does the Alzheimer’s disease brain respond to optomechanical stimuli?: a na...
Monteiro, Francisca Machado; Oliveira, Sofia; Gasik, Michael; Sousa, Nuno; Sotiropoulos, I.; Silva, Filipe Samuel; Carvalho, Óscar Samuel NovaisAlzheimer's disease (AD) is a neurodegenerative condition with enormous social and economic impact at a global scale. Given the inefficacy of the pharmacological treatments developed so far in decelerating/blocking AD pathology, the study and development of so-called alternative (i.e., non-pharmacological) and non-invasive therapies has become one of the major focuses of biomedical research on AD in recent year...
Multi‑mechanical waves against Alzheimer’s disease pathology: a systematic review
Monteiro, Francisca Machado; Sotiropoulos, I.; Carvalho, Óscar Samuel Novais; Sousa, Nuno; Silva, Filipe SamuelAlzheimer’s disease (AD) is the most common cause of dementia, affecting approximately 40 million people worldwide. The ineffectiveness of the available pharmacological treatments against AD has fostered researchers to focus on alternative strategies to overcome this challenge. Mechanical vibrations delivered in different stimulation modes have been associated with marked improvements in cognitive and physical ...
Classificação da condição física e da performance desportiva utilizando espetro...
Monteiro, Francisca MachadoA análise e classificação da condição física e da performance desportiva constituem uma necessidade emergente e cada vez mais requerida, daí que a recolha de informação relevante e o seu processamento sejam essenciais para apoiar uma gestão orientada e personalizada da dieta e do treino praticados pelos atletas. Neste trabalho, é proposta uma metodologia que permite realizar a monitorização dos atletas em point...