Background: A patient recovering from an in-hospital or out-of-hospital cardiac arrest (CA) requires interventions for recovery, particularly for minimising secondary brain injury. Targeted temperature management (TTM) is the intervention with the greatest impact on neurological recovery. Aim: The aim of this systematic review was to describe current TTM in adult CA patients and its impact on functional outcome...
Introdução: Os hábitos alimentares são uma das principais causas modificáveis de doenças crónicas não transmissíveis. A Dieta Mediterrânica é conhecida por ser um padrão alimentar protetor da saúde e sustentável. Nas últimas décadas, Portugal, tem-se distanciado deste padrão alimentar e aumentado o consumo de alimentos ultraprocessados. Objetivos: Avaliar a adesão ao Padrão Alimentar Mediterrânico, o consumo de...
Purpose: To evaluate complete blood count (CBC) parameters in the first week of life as predictive biomarkers for the development of retinopathy of prematurity (ROP). Methods: Multicenter, prospective, observational study of a cohort of preterm infants born with gestational age (GA) < 32 weeks or birth weight < 1500 g in eight Portuguese neonatal intensive care units. All demographic, clinical, and laboratory d...
Given the common anatomical features and similar short-term weight loss outcomes, Biliopancreatic Diversion with Duodenal Switch (BPD/DS) and Single-Anastomosis Duodenoileal bypass with Sleeve gastrectomy (SADI-S) are considered identical bariatric procedures, apart from technical complexity being lower for SADI-S. In the absence of prospective randomized trials or long-term comparative studies the rationale fo...
AimTo evaluate the accuracy of DiaBetter, DiaRem, Ad-DiaRem and 5y-Ad-DiaRem scores' at predicting T2D remission 10 or more years after surgery.MethodsPatients with obesity and T2D (n = 126) submitted to RYGB with 10 or more years of follow-up. It was a unicentric trial. Pre-operative anthropometric and clinical data was retrieved to calculate DiaRem, DiaBetter, Ad-DiaRem and 5y-Ad-DiaRem scores, while a hospit...
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TRUST (social innovation sTRategies for sUSTainability transitions) is a research project that focus on sustainability transition (ST) initiatives in urban and rural Portugal, supported on social learning and innovation. The research aims to investigate forms of social innovation (SI) that can drive community change at local scale, in the context of different social-ecological systems. The analytical process is...
Simple Summary Pharmacological angiogenesis modulation was robustly demonstrated to be a powerful clinical resource in oncotherapy. Adrenocortical carcinomas (ACC) often have a poor prognosis for which therapeutic options are limited. Understanding the mechanisms that regulate adrenocortical angiogenesis both under physiological conditions and in ACC could provide important clues on how these processes could be...
Bortezomib is a first-generation proteasome inhibitor used in the treatment of multiple myeloma. We present a case of a 70-year-old woman with multiple myeloma, who presented thrombotic microangiopathy with multi-organ involvement thrombotic microangiopathy (ocular, cardiac, and renal) after bortezomib initiation. A kidney biopsy confirmed the diagnosis of thrombotic microangiopathy. A temporal relation between...
PROJECT FIGHT-TWO - EDIBLE BAIT VACCINE FOR RABBIT HAEMORRHAGIC DISEASE VIRUS 2 (RHDV2) CONTROL IN WILD RABBITS Carina L. Carvalho1,2, Madalena Monteiro1, Paulo Carvalho1, Paula Mendonça1, Jorge Correia3, Berta São Brás, Conceição Peleteiro 2, Elsa Duarte3, António Mira3, Sandra Branco 3, António Roldão4, Margarida D. Duarte1,2 1-Instituto Nacional de Investigação Agrária e Veterinária Av. da República, Quinta ...