Purpose: We aim to report about effectiveness and safety in the context of our centers’ setting in the management of retinoblastoma with intra-arterial chemotherapy (IAC) in a 5-year retrospective analysis of the Portuguese population. Patients and Methods: Retrospective analysis of consecutive cases of retinoblastoma selected to initiate IAC between 2015 and 2020, at the Portuguese National Reference Center. A...
A necropsia permite que o médico veterinário, através da observação e interpretação das lesões macroscópicas, formule um correto diagnóstico e, consequentemente, possibilita a implementação rápida de adequada terapêutica e/ou de medidas profiláticas. A presente obra é única por apresentar as lesões macroscópicas das doenças mais frequentes no nosso país. Está dividida em capítulos respeitantes aos vários sistem...
INTRODUCTION: Patients under 5 years old with retinoblastoma require close monitoring under anesthesia to ensure early detection of new tumors. They undergo monthly observations after diagnosis and during the first 6 months after treatment, then observations are gradually spaced in time until the age of five. Optical coherence tomography (OCT) is a relatively new exam in monitoring retinoblastoma patients. The ...
Purpose: To evaluate complete blood count (CBC) parameters in the first week of life as predictive biomarkers for the development of retinopathy of prematurity (ROP). Methods: Multicenter, prospective, observational study of a cohort of preterm infants born with gestational age (GA) < 32 weeks or birth weight < 1500 g in eight Portuguese neonatal intensive care units. All demographic, clinical, and laboratory d...
The purpose of this study is to characterize demographically and genetically the Portuguese population with retinoblastoma; to report the clinical stage at presentation and its impact on survival and ocular preservation rate and, finally, to assess the incidence of retinoblastoma in Portugal. Retrospective observational study including children consecutively diagnosed with retinoblastoma at the Portuguese Natio...
Objective: The aim of our study was to characterize the evacuated African patients diagnosed with retinoblastoma and referred to the Portuguese national referral center (Centro Hospital e Universitário de Coimbra, University of Coimbra), identifying inequalities in the stage of diagnosis and prognostic results. Design: Retrospective observational study of evacuated African patients diagnosed with retinoblastoma...
ABSTRACT - Myxomatosis is an emergent disease in the Iberian hare, having been considered a rabbit disease for decades. Genome sequencing of the strains obtained from Iberian hares with myxomatosis showed these to be distinct from the classical ones that circulated in rabbits since the virus introduction in Europe, in 1952. The main genomic difference in this natural recombinant hare myxoma virus (ha-MYXV) is t...
ABSTRACT - Halicephalobus gingivalisis a small saprophytic rhabditid nematode, represented only by females with a typicalrhabditoid oesophagus and one egg in the uterus, capable of infecting vertebrates. This opportunistic parasitepresent in the soil, manure and decaying humus, is thought to penetrate through previous injuries to the mouth,eyes and skin of horses and migrate to various organs. The brain is one ...
Objetivo: Comparar duas modalidades de rastreio de fatores de risco ambliogénicos em crianças numa área urbana. Desenho: Estudo prospetivo. Participantes: crianças das pré-escolas e escolas básicas de uma área urbana. Materiais e métodos: Comparação de dois rastreios de fatores ambliogénicos independentes, de Abril a Setembro de 2014. O rastreio pré-escolar foi realizado com tecnologia de fotorrastreio. O rastr...
As key prey, the wild rabbit downsize constitutes a major drawback on the endangered Iberian lynx (Lynx pardinus) re-introduction in the Iberia. Several captive breeding units mostly located in Alentejo, endeavour the wild rabbit repopulation of depleted areas assigned for the lynx re-introduction. Here we report an RHDV2 outbreak that occurred in early 2016 in a wild rabbit captive breeding unit located in Bar...