7 documents found, page 1 of 1
Effects of Fluoride on Submandibular Glands of Mice: Changes in Oxidative Bioch...
Lima, Leidiane Alencar de Oliveira; Miranda, Giza Hellen Nonato; Aragão, Walessa Alana Bragança; Bittencourt, Leonardo OliveiraMade available in DSpace on 2022-04-29T08:45:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-27; Although fluoride (F) is well-known to prevent dental caries, changes in cell processes in different tissues have been associated with its excessive exposure. Thus, this study aimed to evaluate the effects of F exposure on biochemical, proteomic, and genotoxic parameters of submandibular glands. Twenty ...
Effects of long-term fluoride exposure are associated with oxidative biochemist...
Miranda, Giza Hellen Nonato; De Oliveira Lima, Leidiane Alencar; Bittencourt, Leonardo Oliveira; Dos Santos, Savio MonteiroMade available in DSpace on 2022-04-29T08:46:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; Background Fluoride has become widely used in dentistry because of its effectiveness in caries control. However, evidence indicates that excessive intake interferes with the metabolic processes of different tissues. Thus, this study aimed to investigate the effects of long-term exposure to F on the paro...
Synthesis and biological evaluation of chalcones and derivatives in vitro again...
Anjos, Maricelia Lopes dos; Reis, Herald Souza dos; Bitencourt , Heriberto Rodrigues; Galucio, Natasha Costa da Rocha; Khayat, André SalimThe interest in obtaining chalcones is due to the numerous pharmacological activities described in the literature for these compounds that are intermediates in the biosynthesis of flavonoids. Thus, the synthesis and characterization of several chalcones and derivatives become important for the development of compounds with antiproliferative activity. In this work, ten substances were synthesized, seven chalcone...
Imaging microstructural damage and alveolar bone loss in rats systemically expo...
Lopes, G?ssica de Oliveira; Arag?o, Walessa Alana Bragan?a; Bittencourt, Leonardo Oliveira; Puty, Bruna; Lopes, Armando PereiraThis work was supported by the Brazilian National Council for Scientific and Technological Development (CNPq), Funda??o de Amparo a Pesquisa do Estado do Par? (FAPESPA), and Pr?-Reitoria de Pesquisa e P?s-Gradua??o da UFPA (PROPESP, UFPA, Brazil).; Federal University of Par?. Institute of Biological Sciences. Laboratory of Functional and Structural Biology. Bel?m, PA, Brazil.; Federal University of Par?. Instit...
Piceatannol increases antioxidant defense and reduces cell death in human perio...
Costa, Fl?via P?voa da; Puty, Bruna; Nogueira, Lygia S; Mitre, Geovanni Pereira; Santos, S?vio Monteiro dos; Teixeira, Bruno Jos? BritoFunding: Amazon Foundation of Support for Studies and Research (FAPESPA). Brazilian Federal Agency for Support and Evaluation of Graduate Education (CAPES- finance code 001); Federal University of Par?. Institute of Biological Sciences. Laboratory of Functional and Structural Biology. Bel?m, PA, Brazil / Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas.Laborat?rio de Cultura de T...
Unravelling motor behaviour hallmarks in intoxicated adolescents: methylmercury...
Oliveira, Aline Nascimento; Pinheiro, Alana Miranda; Bel?m-Filho, Ivaldo Jesus Almeida; Fernandes, Luanna Melo Pereira; Cart?genes, Sabrina CarvalhoThis work was funded by Funda??o Amaz?nia de Amparo a Estudos e Pesquisa do Par? (FAPESPA, grant number 160/2014 Edital 006/2014). Bel?m-Filho IJA and Nascimento AS received scholarships from Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES); Universidade Federal do Par?. Faculdade de Ci?ncias Farmac?uticas. Laborat?rio de Farmacologia da Inflama??o e do Comportamento. Bel?m, PA, Brazil.; Univ...
Bothrops moojeni myotoxin-II, a Lys49-phospholipase A2 homologue : an example o...
Stabeli, Rodrigo Guerino; Amui, Saulo França; Sant'Ana, Carolina Dalaqua; Pires, Matheus Godoy; Nomizo, Auro; Monteiro, Marta ChagasMjTX-II, a myotoxic phospholipase A2 (PLA2) homologue from Bothrops moojeni venom, was functionally and structurally characterized. The MjTX-II characterization included: (i) functional characterization (antitumoral, antimicrobial and antiparasitic effects); (ii) effects of structural modifications by 4-bromophenacyl bromide (BPB), cyanogen bromide (CNBr), acetic anhydride and 2-nitrobenzenesulphonyl fluoride (...