20 documents found, page 1 of 2
Diversity and comparative genomic analysis of Pseudomonas syringae pv. actinidi...
Gimranov, Emil; Santos, Marino; Monteiro, Rodrigo; Azeredo, Joana; Santos, Conceição; Moura, LuísaPseudomonas syringae pv. actinidiae is a pandemic agent of bacterial canker in kiwifruit. The virulence of bacteria can be mediated by horizontal gene transfer in a co-evolutionary process with other microorganisms, enriching their genetic repertoire and enhancing adaptation strategies and fitness. Temperate bacteriophages can integrate into bacterial genomes, increasing genetic diversity and potentially improv...
Outer membrane vesicles of carbapenem-resistant clinical Acinetobacter baumanni...
Monteiro, Rodrigo; Alcantud, Beatriz Santamarina; Piersma, Sjouke; Hendrickx, Antoni P. A.; Maaß, Sandra; Becher, Dörte; Azeredo, Joana; Bathoorn, ErikInfections caused by carbapenem-resistant Acinetobacter baumannii (A. baumannii; CRAb) are associated with high patient morbidity and mortality. The serious threat for human health imposed by CRAb was recently underscored by identification of close-to-untouchable carbapenem- and tetracycline-resistant isolates. Since outer membrane vesicles (OMVs) of Gram-negative bacteria may contribute to antimicrobial resist...
Phage-host interaction analysis by flow cytometry allows for rapid and efficien...
Melo, Luís Daniel Rodrigues; Monteiro, Rodrigo; Pires, Diana Priscila Penso; Azeredo, JoanaRecently, phages have become popular as an alternative to antibiotics. This increased demand for phage therapy needs rapid and efficient methods to screen phages infecting specific hosts. Existing methods are time-consuming, and for clinical purposes, novel, quick, and reliable screening methods are highly needed. Flow cytometry (FC) allows a quick differentiation and enumeration of bacterial cell populations a...
Exploitation of a klebsiella bacteriophage receptor-binding protein as a superi...
Nogueira, Catarina; Pires, Diana P.; Monteiro, Rodrigo; Santos, Sílvio Roberto Branco; Carvalho, Carla M.Klebsiella pneumoniae is a Gram-negative bacterium that has become one of the leading causes of life-threatening healthcare-associated infections (HAIs), including pneumonia and sepsis. Moreover, due to its increasingly antibiotic resistance, K. pneumoniae has been declared a global top priority concern. The problem of K. pneumoniae infections is due, in part, to the inability to detect this pathogen rapidly an...
Designing P. aeruginosa synthetic phages with reduced genomes
Pires, Diana Priscila Penso; Monteiro, Rodrigo; Mil-Homens, Dalila; Fialho, Arsénio; Lu, Timothy K.; Azeredo, JoanaIn the era where antibiotic resistance is considered one of the major worldwide concerns, bacteriophages have emerged as a promising therapeutic approach to deal with this problem. Genetically engineered bacteriophages can enable enhanced anti-bacterial functionalities, but require cloning additional genes into the phage genomes, which might be challenging due to the DNA encapsulation capacity of a phage. To ta...
Desenvolvimento de menta e produção de óleo essencial sob diferentes condições ...
Monteiro, RodrigoOrientador: Prof. Dr. Cícero Deschamps; Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Agrárias, Programa de Pós-Graduação em Agronomia. Defesa: Curitiba, 30/03/2009; Inclui bibliografia e anexos; Área de concentração: Produção vegetal
Appropriateness of Radiology Test Requests by an Emergency Department: A Retros...
Martins, Rute; Raimundo, Pedro; Alves, Pedro; Monteiro, Rodrigo; Silva, Luís Duarte; Gomes, André; Afonso, GraçaIntroduction: Imaging tests are essential for diagnosis in the emergency context and convey clinical information that is essential to assess the appropriateness of the tests and improve their interpretation. Therefore, we aimed to analyze the imaging tests requested by the Emergency Department in a district hospital.Material and Methods: We retrospectively analyzed computed tomography and ultrasound scans reque...
Appropriateness of radiology test requests by an emergency department: a retros...
Martins, Rute; Raimundo, Pedro; Alves, Pedro; Monteiro, Rodrigo; Silva, Luís Duarte; Gomes, André; Afonso, GraçaImaging tests are essential for diagnosis in the emergency context and convey clinical information that is essential to assess the appropriateness of the tests and improve their interpretation. Therefore, we aimed to analyze the imaging tests requested by the Emergency Department in a district hospital.
A dimens??o do estudo da ??tica no ensino m??dio t??cnico: uma abordagem com ba...
Monteiro, RodrigoSubmitted by Rodrigo Monteiro (monteiros.adv@hotmail.com) on 2019-02-08T18:27:48Z No. of bitstreams: 3 Disserta????o Rodrigo Monteiro.pdf: 1294520 bytes, checksum: 1d4fecaffc7e326ea6da1bc2aa22c496 (MD5) Anexos Disserta????o.PDF: 1100024 bytes, checksum: 692d84795a4f866558106acf79c33c15 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5); Approved for entry into archive by PPGECH Ci??nci...
Phage therapy of infectious biofilms: challenges and strategies
Melo, Luís Daniel Rodrigues; Pires, Diana P.; Monteiro, Rodrigo; Azeredo, JoanaInfectious biofilms are difficult to target with conventional antibiotherapy due to their intrinsic tolerance to antibiotics. In vitro, ex vivo and in vivo studies have shown great efficacy of bacteriophages (phages) in combating biofilms. However, the tri-dimensional organisation of the biofilm cells inside a polymeric matrix, along with their sessile associated physiology, imposes some difficulties to phage t...