This study aimed at evaluating the antidepressant-like action of the marine alga Solieria filiformis lectin (SfL) and to investigate the participation of the monoaminergic system in this action. For this, male Swiss mice (n=10) were pretreated with intravenous injections (i.v.) of SfL (1, 3 or 9mg/kg) and submitted to open field (OFT), tail suspension (TST), forced swimming (FST), elevated plus-maze (EPMT) and ...
Sulphated polysaccharides are found in several marine organisms and are of great interest in the medical sciences due to their biological properties, such as: immunomodulatory, antiinflammatory and antitumor capacity. Recently, a sulfated polysaccharide of the agarane type, previously characterized by nuclear magnetic resonance, obtained from the marine macroalgae Gracilaria cornea, has demonstrated antinocicep...
MONTEIRO, V. S. Efeito ansiolítico dos polissacarídeos sulfatados da alga marinha vermelha Gracilaria cornea J. Agardh em modelos neurocomportamentais em camundongos. 2014. 72 f. Dissertação (Mestrado em Bioquímica) - Centro de Ciências, Universidade Federal do Ceará, Fortaleza, 2014.; Currently there is an increased interest in developing new therapeutic agents from biologically active molecules present in nat...