Abstract This study aimed to evaluate the in vitro antifungal activity of terpinen-4-ol, tyrosol, and β-lapachone against strains of Coccidioides posadasii in filamentous phase (n = 22) and Histoplasma capsulatum in both filamentous (n = 40) and yeast phases (n = 13), using the broth dilution methods as described by the Clinical and Laboratory Standards Institute, to determine the minimum inhibitory concentrati...
Abstract Recent studies have shown that some drugs that are not routinely used to treat fungal infections have antifungal activity, such as protease inhibitor antiretroviral drugs. This study investigated the in vitro susceptibility of Histoplasma capsulatum var. capsulatum to saquinavir and ritonavir, and its combination with the antifungal itraconazole. The susceptibility assay was performed according to Clin...
This study aimed to evaluate the role of the Amazon River prawn, Macrobrachium amazonicum, as carrier of Candida spp., by analyzing the correlation between Candida spp. from these prawns and their environment (surface water and sediment), through M13-PCR fingerprinting and RAPD-PCR. For this purpose, 27 strains of Candida spp. were evaluated. These strains were recovered from the gastrointestinal tract of adult...
Little information on the epidemiology and clinical characteristics of human parainfluenza virus (HPIV) infections, especially in children from tropical countries, has been published. The aim of this study was to determine the frequency of HPIV infections in children attended at a large hospital in Fortaleza in Northeast Brazil, and describe seasonal patterns, clinical and epidemiological characteristics of the...
Infection with both Human Immunodeficiency Virus (HIV) and Mycobacterium tuberculosis is currently the world's leading cause of death due to infectious agents. We evaluated factors related to the development of tuberculosis (TB) in HIV-infected patients who were being treated at an infectious diseases hospital in Fortaleza, Ceará, Brazil. From January 2004 to December 2005, we made an epidemiological study thro...
O presente estudo objetivou descrever alguns fatores relacionados à positividade de cães para leishmaniose visceral, em área endêmica do Estado do Rio Grande do Norte. Foram analisados 198 cães, dos quais 62 foram recrutados de propriedades rurais e 136 de residências urbanas. O diagnóstico foi realizado através dos testes de imunofluorescência indireta e imunoadsorção enzimática. Dos cães analisados, 45% dos p...
A manutenção de culturas de Malassezia pachydermatis em micotecas é importante para estudos retrospectivos e prospectivos. O objetivo deste trabalho foi avaliar o comportamento de Malassezia pachydermatis frente a diferentes métodos de conservação de culturas. Para tanto, após o processo de identificação, essa levedura foi estocada, por seis e nove meses, em salina e salina com óleo mineral a 28°C, bem como, em...