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Structural and molecular correlates of cognitive aging in the rat
Mota, Cristina; Taipa, Ricardo; das Neves, Sofia Pereira; Monteiro-Martins, Sara; Monteiro, Susana; Palha, Joana Almeida; Sousa, NunoAging is associated with cognitive decline. Herein, we studied a large cohort of old age and young adult male rats and confirmed that, as a group, old rats display poorer spatial learning and behavioral flexibility than younger adults. Surprisingly, when animals were clustered as good and bad performers, our data revealed that while in younger animals better cognitive performance was associated with longer den...
Data: 2019
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Origem: RepositóriUM - Universidade do Minho