2 documents found, page 1 of 1
Invisible for a few but essential for many: the role of Histotechnologists in t...
Magalhães, Gisela; Calisto, Rita; Freire, Catarina; Silva, Regina; Montezuma, Diana; Canberkg, Sule; Schmitt, FernandoDigital pathology (DP) is indisputably the future for histopathology laboratories. The process of digital implementation requires deep workflow reorganisation which involves an interdisciplinary team. This transformation may have the greatest impact on the Histotechnologist (HTL) profession. Our review of the literature has clearly revealed that the role of HTLs in the establishment of DP is being unnoticed and...
Phenotypic impact of deregulated expression of class I histone deacetylases in ...
Neto, Susana; Quintela Vieira, Ana Filipa; Montezuma, Diana; Costa, Natália R.; Antunes, Luís; Baptista, Tiago; Oliveira, Ana IsabelDeregulated expression of histone deacetylases (HDACs) has been implicated in tumorigenesis. Herein, we investigated class I HDACs expression in bladder urothelial cell carcinoma (BUCC), its prognostic value and biological significance. Significantly increased transcript levels of all HDACs were found in BUCC compared to 20 normal mucosas, and these were higher in lower grade and stage tumors. Increased HDAC3 l...