3 documents found, page 1 of 1
Urinary N -methylnicotinamide and β -aminoisobutyric acid predict catch-up grow...
Mayneris-Perxachs, Jordi; Lima, Aldo A.M.; Guerrant, Richard L.; Leite, Álvaro M.; Moura, Alessandra F. Moura; Lima, Noélia L.; Soares, Alberto M.Enteric infections, enteropathy and undernutrition in early childhood are preventable risk factors for child deaths, impaired neurodevelopment, and later life metabolic diseases. However, the mechanisms linking these exposures and outcomes remain to be elucidated, as do biomarkers for identifying children at risk. By examining the urinary metabolic phenotypes of nourished and undernourished children participati...
Prolonged maternal separation induces undernutrition and systemic inflammation ...
Figueiredo, Ítalo Leite; Frota, Priscila B.; Cunha, Davi G. da; Raposo, Ramon da Silva; Canuto, Kildere M.; Andrade, Geanne M. de; Sousa, NunoObjective: Prolonged maternal separation (PMS) in the first 2 wk of life has been associated with poor growth with lasting effects in brain structure and function. This study aimed to investigate whether PMS-induced undernutrition could cause systemic inflammation and changes in nutrition-related hormonal levels, affecting hippocampal structure and neurotransmission in C57BL/6J suckling mice. Methods: This stud...
Zinc treatment ameliorates diarrhea and intestinal inflammation in undernourish...
Queiroz, Camila A. A. de; Fonseca, Said Gonçalves C.; Frota, Priscila B.; Figueiredo, Ítalo L.; Aragão, Karoline Sabóia; Magalhães, Carlos Emanuel C.Background: WHO guidelines recommend zinc supplementation as a key adjunct therapy for childhood diarrhea in developing countries, however zinc’s anti-diarrheal effects remain only partially understood. Recently, it has been recognized that low-grade inflammation may influence stunting. In this study, we examined whether oral zinc supplementation could improve weight, intestinal inflammation, and diarrhea in un...